Protein-peptide interactions play important roles in many cellular processes, including signal
transduction, trafficking, and immune recognition. Protein conformational changes upon …

Peptide-protein interactions are very prevalent, mediating key processes such as signal
transduction and protein trafficking. How can peptides overcome the entropic cost involved …

Peptides mediate up to 40% of protein interactions, their high specificity and ability to bind in
places where small molecules cannot make them potential drug candidates. However …

Peptides have gained increased interest as therapeutic agents during recent years. The
high specificity and relatively low toxicity of peptide drugs derive from their extremely tight …

Peptides mediate up to 40% of known protein-protein interactions in higher eukaryotes and
play a key role in cellular signaling, protein trafficking, immunology, and oncology. However …

The significant work that has been invested toward understanding protein− protein
interaction has not translated into significant advances in structure-based predictions. In …

We review computational models and software tools in current use for the study of protein–
peptide interactions. Peptides and peptide derivatives are growing in interest as therapeutic …

Peptide–protein interactions are prevalent in the living cell and form a key component of the
overall protein–protein interaction network. These interactions are drawing increasing …

Highlights•Accrual of peptide–protein complex structures allowed their detailed
characterization.•This has lead to rapid progress in peptide docking, based on diverse …

Understanding protein-protein association is crucial in revealing the molecular basis of
many biological processes. Here, we describe a theoretical simulation pipeline to study …