Transcription termination of protein-coding genes in eukaryotic cells usually relies on a tight
coordination between the cleavage and polyadenylation of the pre-mRNA, and 5′-3 …

Termination of RNA polymerase II (RNAPII) transcription is a fundamental step of gene
expression that is critical for determining the borders between genes. In budding yeast …

In fission yeast, the RNAi pathway is required for heterochromatin-dependent silencing of
transgene insertions at centromeric repeats and acts together with other pathways to silence …

RNA interference (RNAi) is widespread in eukaryotes and regulates gene expression
transcriptionally or post‐transcriptionally. In fission yeast, RNAi is tightly coupled to template …

Transcription termination of messenger RNA (mRNA) is normally achieved by
polyadenylation followed by Rat1p-dependent 5′-3′ exoribonuleolytic degradation of the …

Fission yeast Cid14, a component of the TRAMP (Cid14/Trf4-Air1-Mtr4 polyadenylation)
complex, polyadenylates nuclear RNA and stimulates degradation by the exosome for RNA …

Transcription termination determines the ends of transcriptional units and thereby ensures
the integrity of the transcriptome and faithful gene regulation. Studies in yeast and human …

Pervasive transcription is a universal phenomenon leading to the production of a plethora of
non-coding RNAs. If left uncontrolled, pervasive transcription can be harmful for genome …

Transcriptome studies on eukaryotic cells have revealed an unexpected abundance and
diversity of noncoding RNAs synthesized by RNA polymerase II (Pol II), some of which …

RNAi is a conserved mechanism in which small RNAs induce silencing of complementary
targets. We have previously identified priRNAs, a class of Dicer-independent small RNAs in …