ABSTRACT From May 1997 to December 2001, a serotype O: 6 multidrug-resistant strain of
Pseudomonas aeruginosa colonized or infected 201 patients in the University Hospital of …

In Pseudomonas aeruginosa many of the clinically relevant resistance mechanisms result
from changes in gene expression as exemplified by the Mex drug efflux pumps, the AmpC β …

Imipenem resistance in Pseudomonas aeruginosa is considered to be associated with loss
of the porin OprD combined with activity of chromosomal β‐lactamase (AmpC), while …

ABSTRACT During a 6-month period, 21 pairs of Pseudomonas aeruginosa isolates
susceptible (pretherapy) and resistant (posttherapy) to antipseudomonal β-lactam antibiotics …

Background Multidrug resistance has become a quandary in the treatment of bacterial
infections. The effect of resistance mutations and the fitness cost on the pathogenicity of …

In order to define the contributions of the mechanisms for carbapenem resistance in clinical
strains of Pseudomonas aeruginosa, we investigated the presence of OprD, the expressions …

We describe the molecular characterization of a multiresistant Pseudomonas aeruginosa
clone causing an outbreak in the intensive care unit (ICU) of a tertiary-care university …

Serotype 012 Pseudomonas aeruginosa resistant to gentamicin (MIC> 4mg/l) and
carbenicillin (MIC> 128 mg/l) occur widely in Europe and are homogeneous in their …

MexAB‐OprM is a multidrug efflux system that contributes to intrinsic and acquired multidrug
resistance in Pseudomonas aeruginosa, the latter as a result of mutational hyperexpression …

We evaluated the roles of the MexAB-OprM efflux pump and β-lactamase in β-lactam
resistance in Pseudomonas aeruginosa by constructing OprM-deficient, OprM basal level …