A little sugar goes a long way: the cell biology of O-GlcNAc
MR Bond, JA Hanover - Journal of Cell Biology, 2015 - rupress.org
Unlike the complex glycans decorating the cell surface, the O-linked β-N-acetyl glucosamine
(O-GlcNAc) modification is a simple intracellular Ser/Thr-linked monosaccharide that is …
(O-GlcNAc) modification is a simple intracellular Ser/Thr-linked monosaccharide that is …
O-GlcNAc cycling: implications for neurodegenerative disorders
BD Lazarus, DC Love, JA Hanover - … journal of biochemistry & cell biology, 2009 - Elsevier
The dynamic post-translational modification of proteins by O-linked N-acetylglucosamine (O-
GlcNAc), termed O-GlcNAcylation, is an important mechanism for modulating cellular …
GlcNAc), termed O-GlcNAcylation, is an important mechanism for modulating cellular …
O-GlcNAc transferase and O-GlcNAcase: achieving target substrate specificity
AK Nagel, LE Ball - Amino acids, 2014 - Springer
O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) catalyze the dynamic cycling of
intracellular, post-translational O-GlcNAc modification on thousands of Ser/Thr residues of …
intracellular, post-translational O-GlcNAc modification on thousands of Ser/Thr residues of …
Protein O-GlcNAcylation: emerging mechanisms and functions
O-GlcNAcylation—the attachment of O-linked N-acetylglucosamine (O-GlcNAc) moieties to
cytoplasmic, nuclear and mitochondrial proteins—is a post-translational modification that …
cytoplasmic, nuclear and mitochondrial proteins—is a post-translational modification that …
Cracking the O-GlcNAc code in metabolism
Nuclear, cytoplasmic, and mitochondrial proteins are extensively modified by O-linked β-N-
acetylglucosamine (O-GlcNAc) moieties. This sugar modification regulates fundamental …
acetylglucosamine (O-GlcNAc) moieties. This sugar modification regulates fundamental …
Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology
K Vaidyanathan, S Durning, L Wells - Critical reviews in …, 2014 - Taylor & Francis
O-linked β-N-acetylglucosamine (O-GlcNAc) is a regulatory post-translational modification of
intracellular proteins. The dynamic and inducible cycling of the modification is governed by …
intracellular proteins. The dynamic and inducible cycling of the modification is governed by …
O-GlcNAcase Expression is Sensitive to Changes in O-GlcNAc Homeostasis
O-linked N-acetylglucosamine (O-GlcNAc) is a post-translational modification involving an
attachment of a single β-N-acetylglucosamine moiety to serine or threonine residues in …
attachment of a single β-N-acetylglucosamine moiety to serine or threonine residues in …
[HTML][HTML] Growing and dividing: how O-GlcNAcylation leads the way
Cell cycle errors can lead to mutations, chromosomal instability, or death; thus, the precise
control of cell cycle progression is essential for viability. The nutrient-sensing post …
control of cell cycle progression is essential for viability. The nutrient-sensing post …
Molecular mechanisms regulating O-linked N-acetylglucosamine (O-GlcNAc)–processing enzymes
The post-translational modification of proteins by O-linked N-acetylglucosamine (O-GlcNAc)
dynamically programmes cellular physiology to maintain homoeostasis and tailor …
dynamically programmes cellular physiology to maintain homoeostasis and tailor …
O-linked β-N-acetylglucosamine (O-GlcNAc): extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress
C Butkinaree, K Park, GW Hart - … et Biophysica Acta (BBA)-General Subjects, 2010 - Elsevier
BACKGROUND: Since its discovery in the early 1980s, O-linked-β-N-acetylglucosamine (O-
GlcNAc), a single sugar modification on the hydroxyl group of serine or threonine residues …
GlcNAc), a single sugar modification on the hydroxyl group of serine or threonine residues …