Bacterial vaccines have made dramatic impacts upon morbidity and mortality caused by a
number of common pathogens, but a vaccine to prevent Staphylococcus aureus infections …

In this review, we examine the current status of S taphylococcus aureus vaccine
development and the prospects for future vaccines. Examination of the clinical trials to date …

Staphylococcus aureus, a prevalent human pathogen and a leading cause of hospital-
acquired infections, is increasingly evolving antibiotic-resistant strains, increasing mortality …

Staphylococcus aureus is one of the most important human pathogens worldwide. Its high
antibiotic resistance profile reinforces the need for new interventions like vaccines in …

Developing a universal vaccine for S. aureus is a top priority but to date we have only had
failures in human clinical trials. Given the plethora of bacterial virulence factors, broad range …

Staphylococcus aureus is a major pathogen in both community and hospital settings. It is a
significant etiological agent to treat in healthcare-related infections due to both its ability to …

Staphylococcus aureus is a common human commensal organism and also a major cause
of nosocomial infections worldwide associated with high death rates, prolonged …

High attack rates and the ability of Staphylococcus aureus to develop resistance to all
antibiotics in medical practice heightens the urgency for vaccine development. S. aureus …

This review considers the reasons why the staphylococcal vaccine trials may have failed,
based on new information about protective immunity against Staphylococcus aureus. The …

Staphylococcus aureus is a leading pathogen in surgical site, intensive care unit, and skin
infections, as well as healthcare-associated pneumonias. These infections are associated …