EGFR mutations are detected comparably in cytologic and surgical pathology specimens of nonsmall cell lung cancer
BACKGROUND: Somatic mutations in the epidermal growth factor receptor (EGFR) are
present in∼ 10% of nonsmall cell lung cancers, and higher in never‐smokers, women, and …
present in∼ 10% of nonsmall cell lung cancers, and higher in never‐smokers, women, and …
EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples
G Ellison, G Zhu, A Moulis, S Dearden… - Journal of clinical …, 2013 - jcp.bmj.com
Aims Activating mutations in the gene encoding epidermal growth factor receptor (EGFR)
can confer sensitivity to EGFR tyrosine kinase inhibitors such as gefitinib in patients with …
can confer sensitivity to EGFR tyrosine kinase inhibitors such as gefitinib in patients with …
High concordance of EGFR mutation status between histologic and corresponding cytologic specimens of lung adenocarcinomas
PL Sun, Y Jin, H Kim, CT Lee, S Jheon… - Cancer …, 2013 - Wiley Online Library
BACKGROUND Activating mutations in the epidermal growth factor receptor (EGFR) in non–
small cell lung carcinoma (NSCLC) are associated significantly with responsiveness to …
small cell lung carcinoma (NSCLC) are associated significantly with responsiveness to …
[HTML][HTML] Detection of EGFR mutation status in lung adenocarcinoma specimens with different proportions of tumor cells using two methods of differential sensitivity
HS Han, S Lim, JY An, KM Lee, KH Choe… - Journal of thoracic …, 2012 - Elsevier
Introduction: To evaluate epidermal growth factor receptor (EGFR) mutation status in lung
adenocarcinoma specimens with different proportions of tumor cells using two methods with …
adenocarcinoma specimens with different proportions of tumor cells using two methods with …
[HTML][HTML] Tissue heterogeneity of EGFR mutation in lung adenocarcinoma
A Sakurada, H Lara-Guerra, N Liu, FA Shepherd… - Journal of Thoracic …, 2008 - Elsevier
Tissue heterogeneity of EGFR gene mutation was studied in 10 formalin-fixed paraffin-
embedded (FFPE) samples from four cases that demonstrated EGFR mutations in snap …
embedded (FFPE) samples from four cases that demonstrated EGFR mutations in snap …
[HTML][HTML] Clinicopathologic characteristics of the EGFR gene mutation in non–small cell lung cancer
AS Tsao, XM Tang, B Sabloff, L Xiao… - Journal of Thoracic …, 2006 - Elsevier
Background The authors sought to define clinicopathologic features associated with
mutations of the epidermal growth factor receptor (EGFR) gene in non–small cell lung …
mutations of the epidermal growth factor receptor (EGFR) gene in non–small cell lung …
EGFR mutations in lung adenocarcinomas: clinical testing experience and relationship to EGFR gene copy number and immunohistochemical expression
Lung adenocarcinomas responsive to epidermal growth factor receptor (EGFR) tyrosine
kinase inhibitors possess EGFR mutations and often increased EGFR copy number. We …
kinase inhibitors possess EGFR mutations and often increased EGFR copy number. We …
EGFR and KRAS mutations in lung carcinoma Molecular testing by using cytology specimens
S Billah, J Stewart, G Staerkel, S Chen… - Cancer …, 2011 - Wiley Online Library
BACKGROUND: The aim of this study was to validate clinical utilization of routinely prepared
cytology specimens for molecular testing to detect EGFR or KRAS mutations in lung cancer …
cytology specimens for molecular testing to detect EGFR or KRAS mutations in lung cancer …
[HTML][HTML] Detection of EGFR gene mutations in non-small cell lung cancer: lessons from a single-institution routine analysis of 1,403 tumor samples
A Vallee, C Sagan, AG Le Loupp… - International …, 2013 - spandidos-publications.com
Activating mutations of the epidermal growth factor receptor (EGFR) in lung tumors are
associated with a dramatic response to tyrosine kinase inhibitors. Therefore, routine analysis …
associated with a dramatic response to tyrosine kinase inhibitors. Therefore, routine analysis …
Evaluation of denaturing high‐performance liquid chromatography as a rapid detection method for identification of epidermal growth factor receptor mutations in …
BACKGROUND. Somatic mutations of the epidermal growth factor receptor (EGFR) gene in
nonsmall‐cell lung cancer (NSCLC) may predict responsiveness to tyrosine kinase …
nonsmall‐cell lung cancer (NSCLC) may predict responsiveness to tyrosine kinase …
相关搜索
- nonsmall cell lung cancer
- egfr mutations pathology specimens
- cell lung cancer samples
- small cell lung cancer
- egfr mutation status
- egfr mutations tumor cells
- tissue heterogeneity egfr mutation
- egfr mutations immunohistochemical expression
- egfr mutation testing
- cytology samples lung cancer
- high concordance lung adenocarcinomas
- tumour tissue lung cancer
- growth factor receptor mutations
- differential sensitivity mutation status
- growth factor liquid chromatography
- egfr and kras mutations