Although Snail is essential for disassembly of adherens junctions during epithelial–
mesenchymal transitions (EMTs), loss of adherens junctions in Drosophila melanogaster …

Invagination of the epithelial cell sheet of the prospective mesoderm in Drosophila
gastrulation is a well-studied, relatively simple morphogenetic event that results from …

Actomyosin contractility affects cellular organization within tissues in part through the
generation of mechanical forces at sites of cell–matrix and cell–cell contact. While increased …

Epithelial–mesenchymal transitions play key roles in development and cancer and entail the
loss of epithelial polarity and cell adhesion. In this study, we use quantitative live imaging of …

Tissue morphogenesis relies on the coordinated action of actin networks, cell–cell
adhesions, and cell–extracellular matrix (ECM) adhesions. Such coordination can be …

Remodeling of cell-cell junctions drives cell intercalation that causes tissue movement
during morphogenesis through the shortening and growth of bicellular junctions. The growth …

Epithelial cells assemble specialized actomyosin structures at E-Cadherin–based cell–cell
junctions, and the force exerted drives cell shape change during morphogenesis. The …

During epithelial contraction, cells generate forces to constrict their surface and,
concurrently, fine-tune the length of their adherens junctions to ensure force transmission …

Embryogenesis requires cells to change shape and move without disrupting epithelial
integrity. This requires robust, responsive linkage between adherens junctions and the …

Actomyosin II contractility in epithelial cell plays an essential role in tension-dependent
adhesion strengthening. One key unsettling question is how cellular contraction transmits …