Effect of inter-species, gender, and breeding on the mechanical behavior of brain tissue

F Pervin, WW Chen - NeuroImage, 2011 - Elsevier
Mechanical response of brain tissue deforming at high rates are needed to build high-fidelity
computer models for traumatic brain injury (TBI) studies. Different types of mammalian brains …

Dynamic mechanical response of bovine gray matter and white matter brain tissues under compression

F Pervin, WW Chen - Journal of biomechanics, 2009 - Elsevier
Dynamic responses of brain tissues are needed for predicting traumatic brain injury (TBI).
We modified a dynamic experimental technique for characterizing high strain-rate …

[HTML][HTML] Material properties of human brain tissue suitable for modelling traumatic brain injury

DB MacManus, M Ghajari - Brain Multiphysics, 2022 - Elsevier
Finite element (FE) brain models have revolutionised research on the biomechanics of
traumatic brain injury (TBI). The accuracy and reliability of results arising from brain models …

[HTML][HTML] Towards animal surrogates for characterising large strain dynamic mechanical properties of human brain tissue

DB MacManus, A Menichetti, B Depreitere, N Famaey… - Brain Multiphysics, 2020 - Elsevier
The regional dynamic mechanical properties of mouse, rat, pig, and human brain tissue
were compared directly in this first-of-its-kind study. Our results suggest the use of pig or …

Inertia effects on characterization of dynamic response of brain tissue

B Sanborn, X Nie, W Chen, T Weerasooriya - Journal of biomechanics, 2012 - Elsevier
Modeling and simulation of traumatic brain injury (TBI) resulted from collision or blast
loading requires characterization of mechanical response over a wide range of loading rates …

Region and species dependent mechanical properties of adolescent and young adult brain tissue

DB MacManus, B Pierrat, JG Murphy, MD Gilchrist - Scientific reports, 2017 - nature.com
Traumatic brain injuries, the leading cause of death and disability in children and young
adults, are the result of a rapid acceleration or impact of the head. In recent years, a global …

Viscoelastic properties of the rat brain in the sagittal plane: effects of anatomical structure and age

JD Finan, BS Elkin, EM Pearson, IL Kalbian… - Annals of biomedical …, 2012 - Springer
Rat is the most commonly used animal model for the study of traumatic brain injury. Recent
advances in imaging and computational modeling technology offer the promise of …

Investigation of cross-species scaling methods for traumatic brain injury using finite element analysis

T Wu, J Antona-Makoshi, A Alshareef… - Journal of …, 2020 - liebertpub.com
Scaling methods are used to relate animal exposure data to humans by determining
equivalent biomechanical impact conditions that result in similar tissue-level mechanics for …

A comprehensive experimental study on material properties of human brain tissue

X Jin, F Zhu, H Mao, M Shen, KH Yang - Journal of biomechanics, 2013 - Elsevier
A comprehensive study on the biomechanical response of human brain tissue is necessary
to investigate traumatic brain injury mechanisms. Published brain material property studies …

Measurement of viscoelastic properties of injured mouse brain after controlled cortical impact

Y Chen, S Qiu, C Wang, X Li, Y Tang, Y Feng - Biophysics Reports, 2020 - Springer
Mechanical properties of brain tissue can provide vital information for understanding the
mechanism of traumatic brain injury (TBI). As mouse models were commonly adopted for TBI …