[HTML][HTML] Progress in regenerative medicine: exploring autologous platelet concentrates and their clinical applications

L Giannotti, B Di Chiara Stanca, F Spedicato, P Nitti… - Genes, 2023 - mdpi.com
The goal of regenerative medicine is to achieve tissue regeneration. In the past, commonly
used techniques included autologous or allogeneic transplantation and stem cell therapy …

Novel therapeutic approaches in utilizing platelet lysate in regenerative medicine: Are we ready for clinical use?

M Zamani, Y Yaghoubi… - Journal of cellular …, 2019 - Wiley Online Library
Hemoderivative materials are used to treat different diseases. These derivatives include
platelet‐rich plasma, serum, platelet gel, and platelet lysate (PL). Among them, PL contains …

Autologous platelet-rich plasma for wound and osseous healing: a review of the literature and commercially available products

TS Roukis, T Zgonis, B Tiernan - Advances in therapy, 2006 - Springer
The application of autologous platelets that have been sequestered, concentrated, and
mixed with thrombin to create growth factor-concentrated, autologous platelet-rich plasma …

Platelet rich plasma therapy: inflammatory molecules involved in tissue healing.

E Galliera, MM Corsi, G Banfi - Journal of biological regulators and …, 2012 - europepmc.org
Inflammation represents a fundamental aspect of the healing process. Besides their primary
role in hemostasis, platelets play an active role in the immunological and inflammatory …

Platelets in regeneration

K Stellos, S Kopf, A Paul, JU Marquardt… - … in thrombosis and …, 2010 - thieme-connect.com
Platelets, as the first cellular response after disruption of vascular and/or tissue integrity,
cover any existing injury within our body. But is the regenerative potential of platelets limited …

Platelet-derived factors involved in tissue repair—from signal to function

L Mazzucco, P Borzini, R Gope - Transfusion medicine reviews, 2010 - Elsevier
Topical treatment with platelet derivatives has increasingly been described as being
capable of accelerating wound healing and to aid in tissue repair. In vitro data indicate that …

Bone and wound healing augmentation with platelet-rich plasma

SE Smith, TS Roukis - Clinics in Podiatric Medicine and Surgery, 2009 - Elsevier
Over the past two decades, autologous platelets that have been sequestered, concentrated,
and mixed with thrombin to generate growth factor–concentrated platelet-rich plasma for …

Generation of a pool of human platelet lysate and efficient use in cell culture

K Schallmoser, D Strunk - Basic cell culture protocols, 2013 - Springer
Human platelets represent a promising source of bioactive substances as growth factors not
just for in vivo wound healing and tissue repair, but also for the expansion of human stem …

Platelet-rich plasma: a review of biology and applications in plastic surgery

BL Eppley, WS Pietrzak, M Blanton - Plastic and reconstructive …, 2006 - journals.lww.com
Healing of hard and soft tissue is mediated by a complex array of intracellular and
extracellular events that are regulated by signaling proteins, a process that is, at present …

[HTML][HTML] Effect of platelet lysate on human cells involved in different phases of wound healing

M Chiara Barsotti, P Losi, E Briganti, E Sanguinetti… - PloS one, 2013 - journals.plos.org
Background Platelets are rich in mediators able to positively affect cell activity in wound
healing. Aim of this study was to characterize the effect of different concentrations of human …