Tubuloinferstitial fibrosis is a final common pathway for progressive renal injury in
most'inflammatory'and'non-inflammatory'glomerulopathies. Indeed, the level of …

Progressive renal failure results from a triad of glomerulosclerosis, tubulointerstitial fibrosis
and vascular sclerosis. The mechanisms by which tubules are injured, and by which the …

Tubulointerstitial fibrosis invariably accompanies the course of chronic renal failure towards
end-stage renal disease. Tubular epithelial cells, the predominant cell type in the …

Tubulointerstitial fibrosis (TIF) is the hallmark of chronic kidney disease and best predictor of
renal survival. Many different cell types contribute to TIF progression including tubular …

Mechanisms of tubulointerstitial fibrosis : Current Opinion in Nephrology and Hypertension
Mechanisms of tubulointerstitial fibrosis : Current Opinion in Nephrology and Hypertension …

Detailed histomorphometric analysis of human biopsy tissue over the last 30 years has
convincingly demonstrated that preservation of the tubulointerstitial compartment of the …

Tubulointerstitial damage and progression of renal failure. The present work reviews the
mechanisms and close association between glomerular and tubular damage and its …

Tubulointerstitial damage, in progressive chronic renal disease of all types, arises because
of a complex interplay between factors in the tubular lumen, tubular epithelial cells …

Although chronic progressive tubulointerstitial (TI) disease plays a critical role in the
outcome of patients with primary glomerular lesions, the basic mechanisms that generate …

A vast amount of evidence, based upon human renal biopsy material, indicates that the
presence of tubular atrophy and interstitial fibrosis is a better indicator of outcome of renal …