Background Anatomical connectivity between the thalamus and cortex, including the
prefrontal cortex (PFC), is abnormal in schizophrenia. Overlapping phenotypes, including …

Background Executive cognitive functions, including working memory, cognitive flexibility,
and inhibition, are impaired in schizophrenia. Executive functions rely on coordinated …

The thalamus is a highly connected subcortical structure that relays and integrates sensory
and cortical information, which is critical for coherent and accurate perceptual awareness …

BackgroundCoordination between the thalamus and cortex is necessary for efficient
processing of sensory information and appears disrupted in schizophrenia. The significance …

Background There is considerable evidence that the thalamus is abnormal in psychotic
disorders. Resting-state functional magnetic resonance imaging has revealed an intriguing …

Schizophrenia has long been framed as a disorder of altered brain connectivity, with
dysfunction in thalamocortical circuity potentially playing a key role in the development of the …

Schizophrenia is a devastating neuropsychiatric syndrome associated with distributed brain
dysconnectivity that may involve large-scale thalamo-cortical systems. Incomplete …

Schizophrenia is hypothesized to arise from disrupted brain connectivity. This
“dysconnectivity hypothesis” has generated interest in discovering whether there is …

Background Recent genetic and imaging analyses of large datasets suggested that common
biological substrates exist across psychiatric diagnoses. Functional connectivity (FC) …

Background The striatum is abnormal in schizophrenia and possibly represents a common
neurobiological mechanism underlying psychotic disorders. Resting-state functional …