Comparison of fixed concentration and fixed ratio options for testing susceptibility of gram-negative bacilli to piperacillin and piperacillin/tazobactam

MA Pfaller, AL Barry, PC Fuchs, EH Gerlach… - European Journal of …, 1992 - Springer
Piperacillin combined with tazobactam was tested at both a fixed ratio (8: 1) and fixed
tazobactam concentration (4 µg/ml) against 2,685 consecutively isolated gram-negative …

Comparative antimicrobial activity of piperacillin-tazobactam tested against more than 5000 recent clinical isolates from five medical centers a reevaluation after five …

SA Marshall, KE Aldridge, SD Allen, PC Fuchs… - … and infectious disease, 1995 - Elsevier
Piperacillin combined with tazobactam at a fixed concentration (4 μg/ml) and a ratio (8: 1)
was tested against 5029 aerobic isolates and 447 fastidious organisms, including …

In vitro activity of piperacillin/tazobactam against isolates from patients enrolled in clinical trials

NA Kuck, NV Jacobus, MD Spengler… - International journal of …, 1996 - Elsevier
The in vitro activity of piperacillin alone or titrated with a constant concentration of 4 μg/ml
tazobactam was evaluated against 3962 baseline pathogens isolated from 1899 patients …

Prediction of piperacillin-tazobactam susceptibility among Enterobacteriaceae, Pseudomonas aeruginosa, and other bacteria using ticarcillin-clavulanic acid …

RN Jones, LD Sutton, HF Cantrell… - … microbiology and infectious …, 1994 - Elsevier
The ability of various in vitro β-lactam susceptibility test results to predict the susceptibility of
piperacillin-tazobactam (a new β-lactam-β-lactamase inhibitor combination) was assessed …

Studies to optimize the in vitro testing of piperacillin combined with tazobactam (YTR 830)

RN Jones, AL Barry - Diagnostic microbiology and infectious disease, 1989 - Elsevier
The combination of piperacillin and the beta-lactamase inhibitor tazobactam (formerly YTR
830) was studied to determine optimal disk concentrations and dilution testing conditions. In …

Comparative in-vitro activity of piperacillin-tazobactam against recent clinical isolates, a Dutch national multicentre study

EE Stobberingh, DM Maclaren… - Journal of …, 1994 - academic.oup.com
In this Dutch national survey piperacillin-tazobactam had a MIC90of≤ 8 mg/L for
Enterobacteriaceae (Enterobacter cloacae excluded) and Pseudomonas aeruginosa, 64 …

Multicentre survey of the comparative in-vitro activity of piperacillin/tazobactam against bacteria from hospitalized patients in the British Isles

HY Chen, G Bonfiglio, M Allen, D Piper… - Journal of …, 1993 - academic.oup.com
Abstract Twenty-nine British and Irish hospitals each collected up to 300 bacterial isolates
from in-patients. The organisms were identified by an appropriate API system or, for …

Expanded studies of piperacillin/tazobactam formulations: variations among branded product lots and assessment of 46 generic lots

GJ Moet, AA Watters, HS Sader, RN Jones - Diagnostic microbiology and …, 2009 - Elsevier
The experience with analyzing the potency of piperacillin/tazobactam generic formulations
by a precise multiorganism in vitro assay was expanded to 46 lots (29 manufacturers, 17 …

The activity of piperacillin/tazobactam against clinical isolates collected in 20 UK centres and the design of a disc test for susceptibility testing

DS Reeves, HA Holt, MJ Bywater… - Journal of …, 1993 - academic.oup.com
The in-vitro activities of piperacillin plus tazobactam at ratios of 4: 1, 8: 1 and 16: 1 were
determined against 952 non-copy clinical aerobic bacterial isolates collected from 20 UK …

Comparative activity of piperacillin/tazobactam against 5625 isolates from hospitalised patients

L Verbist, J Verhaegen, C Wounters… - Journal of …, 1996 - academic.oup.com
The comparative activities of piperacillin/tazobactam and other antibiotics against 5625
Gram-negative and Gram-positive bactena freshly isolated from hospitalized patients was …