Context.—Clinical next-generation sequencing (NGS) is being rapidly adopted, but analysis
and interpretation of large data sets prompt new challenges for a clinical laboratory setting …

Context.—Next-generation sequencing (NGS) is a technology being used by many
laboratories to test for inherited disorders and tumor mutations. This technology is new for …

Bioinformatics pipelines are an integral component of next-generation sequencing (NGS).
Processing raw sequence data to detect genomic alterations has significant impact on …

Context The higher throughput and lower per-base cost of next-generation sequencing
(NGS) as compared to Sanger sequencing has led to its rapid adoption in clinical testing …

Context Although next-generation sequencing (NGS) can revolutionize molecular
diagnostics, several hurdles remain in the implementation of this technology in clinical …

Context.—Next-generation sequencing (NGS) is revolutionizing the discipline of laboratory
medicine, with a deep and direct impact on patient care. Although it empowers clinical …

The rapid development of next-generation sequencing (NGS) technology, including
advances in sequencing chemistry, sequencing technologies, bioinformatics, and data …

Context.—Title 45, section 164.524 of the Code of Federal Regulations states that health
care systems must provide patient health records upon that patient's request. For complex …

BACKGROUND Next generation sequencing (NGS)-based assays continue to redefine the
field of genetic testing. Owing to the complexity of the data, bioinformatics has become a …

The field of DNA sequencing experienced a transformational shift beginning in 2005 with the
introduction of the first high-throughput, massively parallel DNA sequencing platform that …