Kidney fibrosis is the unavoidable consequence of chronic kidney disease irrespective of the
primary underlying insult. It is a complex phenomenon governed by the interplay between …

Epithelial-mesenchymal transition (EMT) has become widely accepted as a mechanism by
which injured renal tubular cells transform into mesenchymal cells that contribute to the …

Epithelial-mesenchymal transition (EMT) is described as the process in which injured renal
tubular epithelial cells undergo a phenotype change, acquiring mesenchymal characteristics …

All types of progressive chronic kidney disease (CKD) inevitably induce renal fibrosis, the
hallmark of which is the activation and accumulation of a large number of matrix-producing …

Abstract Epithelial-mesenchymal transition (EMT), a process by which differentiated
epithelial cells undergo a phenotypic conversion that gives rise to the matrix-producing …

Tubulointerstitial injury is one of the hallmarks of renal disease. In particular, interstitial
fibrosis has a prominent role in the development and progression of kidney injury. Collagen …

Mature tubular epithelial cells in adult kidney can undergo epithelial-to-mesenchymal
transition (EMT), a phenotypic conversion that is fundamentally linked to the pathogenesis of …

The hypothesis that epithelial–mesenchymal transition (EMT) might be a contributor to the
accumulation of fibroblasts and myofibroblasts (MFs) in the kidney during fibrogenesis was …

Obstructive nephropathy is a major cause of renal failure, particularly in newborn babies and
children. After urinary tract obstruction, and under the influence of mechanical forces and …

Epithelial to mesenchymal transition (EMT) is a central mechanism for diversifying the cells
found in complex tissues. This dynamic process helps organize the formation of the body …