The safety of the most widely prescribed antiasthma drugs, &adrenoceptor agonists, has
recently been questioned. Zssues such as their suitability for longterm and regular …

Several studies suggested an association between the regular use of β 2-agonists and
asthma deaths. Whether this association represents adverse effects of β-agonist use or is …

The introduction of long-acting beta agonists (LABAs) was considered a major advance in
bronchodilator therapy with evidence that their use led to improved lung function and quality …

There has been a real interest recently in developing once-daily β2-adrenoceptor agonists
(ultra-long-acting β 2-adrenoceptor agonists [ultra-LABAs]) for treating asthma and chronic …

Asthma was originally thought to be associated with an intrinsic defect in β 2ADR (β 2-
adrenoceptor) function, tipping the balance towards parasympathetic bronchoconstriction …

The β-adrenoceptor agonists (β-agonists) have been used to relieve bronchoconstriction for
at least 5000 years. β-agonists are based on adrenaline and early forms, such as …

Abstract β2-adrenoceptor agonists, often used in combination with corticosteroids, have
been extensively used for the treatment of asthma. However, concerns have been raised …

New long-acting beta 2-adrenoceptor agonists, salmeterol and formoterol, have recently
been marketed for treatment of asthma, but studies comparing the clinical efficacy of the two …

The current mainstay of asthma treatment relies on two distinct categories of drugs,
bronchodilators, of which the most potent are thefl-adrenoceptor agonists, and anti …

Background. An effective, long-acting bronchodilator could benefit patients with asthma who
have symptoms not controlled by antiinflammatory drugs. We compared a new long-acting …