The behavioral evidence for dopaminergic modulation of prefrontal cognitive functioning is
reviewed. The experimental studies in rats, monkeys, and humans that highlight the inverted …

The dopamine innervation of the prefrontal cortex is functionally as well as anatomically
specific. Dopamine-immunopositive terminals form symmetrical, presumed inhibitory …

This study examined the effects of depletion of dopamine from the caudate nucleus of the
common marmoset (Callithrix jacchus), on tasks sensitive to prefrontal damage (attentional …

The effects of excitotoxic lesions of the prefrontal cortex on behavioural, neurochemical and
molecular indices of dopamine function in the caudate nucleus were studied in the …

An inverted-U mechanism has been proposed to explain findings that both under-and
overstimulation of dopamine (DA) receptors in medial prefrontal cortex (mPFC) result in …

Substantial depletion of dopamine in a circumscribed region of the prefrontal cortex of the
rhesus monkey produces a deficit in performance on a spatial delayed alternation task …

Dopamine (DA) acts as a key neurotransmitter in the brain. Numerous studies have shown
its regulatory role for motor and limbic functions. However, in the early stages of Parkinson's …

It is well recognised that patients with Parkinson's disease exhibit cognitive deficits, even in
the earliest disease stages. Whereas, l-DOPA therapy in early Parkinson's disease is …

This chapter will review the basic neurobiology of the dopamine (DA) system in the
prefrontal cortex (PFC) and its functional role in cognition. It will consider the properties of …

The neurochemical modulation of prefrontal cortical function is reviewed with special
reference to the ascending dopaminergic and serotoninergic projections. Evidence is …