Myocardial extracellular K+ and H+ increase and noradrenaline release as possible cause of early arrhythmias following acute coronary artery occlusion in pigs

C Franz, L Bös, R Bissig, R Lang, M Schramm - Journal of molecular and …, 1980 - Elsevier
In 22 young domestic pigs, after thoracotomy, the distal half of the ramus descendens
anterior of the left coronary artery was occluded. This caused an ischemia affecting about …

Extracellular potassium activity changes in the canine myocardium after acute coronary occlusion and the influence of beta-blockade

V Wiegand, M Güggi, W Meesmann… - Cardiovascular …, 1979 - academic.oup.com
Extracellular potassium activity before and after coronary occlusion was measured in the
canine heart by means of potassium-selective surface electrodes. In the ischaemic …

[引用][C] Extracellular potassium accumulation during myocardial ischemia: implications for arrhythmogenesis

J Weiss, KI Shine - Journal of molecular and cellular cardiology, 1981 - Elsevier
During ischemia a rapid loss of potassium(K+) from myocardium occurs [B]. Recently studies
using intramyocardial and surface K+ sensitive electrodes have demonstrated increases in …

Effect of acute coronary artery occlusion on local myocardial extracellular K+ activity in swine.

JL Hill, LS Gettes - Circulation, 1980 - Am Heart Assoc
We studied the time course, magnitude and homogeneity of the change in extracellular
myocardial potassium activity after acute ligation of the left anterior descending coronary …

Ischaemia-induced and reperfusion-induced arrhythmias differ in their sensitivity to potassium: implications for mechanisms of initiation and maintenance of ventricular …

MJ Curtis, DJ Hearse - Journal of molecular and cellular cardiology, 1989 - Elsevier
The effects of four different K+ concentrations (2, 4, 6 or 8 mm) on arrhythmias resulting from
ischaemia, and from reperfusion (after 3, 5, 7, 10, 15 or 30 min of ischaemia), in isolated …

Injury current and gradients of diastolic stimulation threshold, TQ potential, and extracellular potassium concentration during acute regional ischemia in the isolated …

R Coronel, FJ Wilms-Schopman, T Opthof… - Circulation …, 1991 - Am Heart Assoc
During acute regional myocardial ischemia, a" current of injury" flows between the ischemic
and the normal tissue. Its direction and magnitude change during the cardiac cycle. During …

[引用][C] Heterogeneity in extracellular potassium concentration during early myocardial ischaemia and reperfusion: implications for arrhythmogenesis

R Coronel - Cardiovascular research, 1994 - academic.oup.com
Ruben Coronel he acute phase of myocardial ischaemia is associated with a high incidence
of life threatening ventricular T arrhythrnias. I4 These early arrhythmias occur in two distinct …

Heterogeneities in [K+]o and TQ Potential and the Inducibility of Ventricular Fibrillation During Acute Regional Ischemia in the Isolated Perfused Porcine Heart

R Coronel, FJG Wilms-Schopman, LRC Dekker… - Circulation, 1995 - Am Heart Assoc
Background The relation between the inducibility of ventricular fibrillation (VF) and
heterogeneity of the extracellular potassium concentration ([K+] o) and of TQ potential is …

Late ventricular arrhythmias during acute regional ischemia in the isolated blood perfused pig heart Role of electrical cellular coupling

JR de Groot, FJG Wilms-Schopman… - Cardiovascular …, 2001 - academic.oup.com
Objective: Acute ischemia comes with two phases of life-threatening arrhythmias, early
(within 10 minutes, 1A) and late (after about 15 minutes, 1B). The mechanism of the latter is …

Ionic basis of ventricular arrhythmias in remodeled rat heart during long-term myocardial infarction

F Aimond, JL Alvarez, JM Rauzier… - Cardiovascular …, 1999 - academic.oup.com
Objective: Deleterious electrical abnormalities evolve during myocardial infarction. The goal
of this study was to analyse current changes during the late decompensated phase of heart …