[HTML][HTML] The dark side of the gut: Virome–host interactions in intestinal homeostasis and disease

Y Li, SA Handley, MT Baldridge - Journal of Experimental Medicine, 2021 - rupress.org
The diverse enteric viral communities that infect microbes and the animal host collectively
constitute the gut virome. Although recent advances in sequencing and analysis of …

Enteric virome sensing—its role in intestinal homeostasis and immunity

RN Metzger, AB Krug, K Eisenächer - Viruses, 2018 - mdpi.com
Pattern recognition receptors (PRRs) sensing commensal microorganisms in the intestine
induce tightly controlled tonic signaling in the intestinal mucosa, which is required to …

The intestinal virome and immunity

JA Neil, K Cadwell - The Journal of Immunology, 2018 - journals.aai.org
The composition of the human microbiome is considered a major source of interindividual
variation in immunity and, by extension, susceptibility to diseases. Intestinal bacteria have …

Virome–host interactions in intestinal health and disease

SU Seo, MN Kweon - Current opinion in virology, 2019 - Elsevier
The enteric virome consists largely of bacteriophages and prophages related to commensal
bacteria. Bacteriophages indirectly affect the host immune system by targeting their …

Gut inflammation and immunity: what is the role of the human gut virome?

A Focà, MC Liberto, A Quirino… - Mediators of …, 2015 - Wiley Online Library
The human virome comprises viruses that infect host cells, virus‐derived elements in our
chromosomes, and viruses that infect other organisms, including bacteriophages and plant …

The human intestinal virome in health and disease

SR Carding, N Davis, L Hoyles - Alimentary pharmacology & …, 2017 - Wiley Online Library
Background The human virome consists of animal‐cell viruses causing transient infections,
bacteriophage (phage) predators of bacteria and archaea, endogenous retroviruses and …

The role of virome in the gastrointestinal tract and beyond

K Tiamani, S Luo, S Schulz, J Xue… - FEMS Microbiology …, 2022 - academic.oup.com
The human gut virome is comprised of diverse commensal and pathogenic viruses. The
colonization by these viruses begins right after birth through vaginal delivery, then continues …

Gut virome and inflammatory bowel disease

LR Lopetuso, G Ianiro, F Scaldaferri… - Inflammatory Bowel …, 2016 - academic.oup.com
Gut virome has been shown to yield some beneficial effects on humans, being deeply
involved in physiology, inflammation, immunity, and disease. Together with transkingdom …

Crosstalk between the intestinal virome and other components of the microbiota, and its effect on intestinal mucosal response and diseases

NA Clinton, SA Hameed, EK Agyei… - Journal of …, 2022 - Wiley Online Library
In recent years, there has been ample evidence illustrating the effect of microbiota on gut
immunity, homeostasis, and disease. Most of these studies have engaged more efforts in …

[HTML][HTML] The virome in host health and disease

K Cadwell - Immunity, 2015 - cell.com
The mammalian virome includes diverse commensal and pathogenic viruses that evoke a
broad range of immune responses from the host. Sustained viral immunomodulation is …