LncRNA MALAT1 promotes lung cancer proliferation and gefitinib resistance by acting as a miR-200a sponge

C Feng, Y Zhao, Y Li, T Zhang, Y Ma, Y Liu - … de Bronconeumología (English …, 2019 - Elsevier
Introduction Lung cancer is a major public health problem, as the second causes of cancer
related death worldwide, with relatively low survival rates, and accessible drug resistance …

The lncRNA MALAT1 contributes to non‐small cell lung cancer development via modulating miR‐124/STAT3 axis

S Li, Z Mei, HB Hu, X Zhang - Journal of Cellular Physiology, 2018 - Wiley Online Library
lncRNAs can exert many biological effects in several cancer types. MALAT1 is a kind of
lncRNA which is greatly overexpressed in several tumors including non‐small cell lung …

[HTML][HTML] LncRNA MALAT1 exerts oncogenic functions in lung adenocarcinoma by targeting miR-204

J Li, J Wang, Y Chen, S Li, M Jin, H Wang… - American journal of …, 2016 - ncbi.nlm.nih.gov
Accumulating evidence indicates that the lncRNAs play a critical role in cancer progression
and metastasis. In this study, we found that MALAT1 upregulation was associated with larger …

MALAT1: a potential biomarker in cancer

ZX Li, QN Zhu, HB Zhang, Y Hu, G Wang… - Cancer management …, 2018 - Taylor & Francis
Purpose The research of long non-coding RNAs (lncRNAs) has become a new passion with
the discovery of abundant new lncRNAs and extensive investigation of their roles in various …

LncRNA MALAT1 accelerates non‐small cell lung cancer progression via regulating miR‐185‐5p/MDM4 axis

D Wang, S Zhang, M Zhao, F Chen - Cancer medicine, 2020 - Wiley Online Library
Non‐small cell lung cancer (NSCLC) is the commonest malignancy with high death rate
around the world. LncRNA metastasis‐associated lung adenocarcinoma transcript 1 …

[HTML][HTML] LncRNA MALAT1 depressed chemo-sensitivity of NSCLC cells through directly functioning on miR-197-3p/p120 catenin axis

T Yang, H Li, T Chen, H Ren, P Shi, M Chen - Molecules and cells, 2019 - Elsevier
This study was aimed to explore if lncRNA MALAT1 would modify chemo-resistance of non-
small cell lung cancer (NSCLC) cells by regulating miR-197-3p and p120 catenin (p120 …

[HTML][HTML] LncRNA MALAT1 promotes breast cancer progression and doxorubicin resistance via regulating miR-570–3p

X Yue, W Wu, M Dong, M Guo - Biomedical journal, 2021 - Elsevier
Background Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long
non-coding RNA (lncRNA) that regulates disease progression in various types of cancers …

[HTML][HTML] Novel insight into MALAT-1 in cancer: Therapeutic targets and clinical applications

D Ren, H Li, R Li, J Sun, P Guo, H Han… - Oncology …, 2016 - spandidos-publications.com
Long non-protein-coding RNAs (lncRNAs) are emerging as important gene expression
regulators that are linked to various biological processes at the post‑transcriptional and …

LncRNA MALAT1 promotes migration and invasion of non-small-cell lung cancer by targeting miR-206 and activating Akt/mTOR signaling

Y Tang, GM Xiao, YJ Chen, Y Deng - Anti-Cancer Drugs, 2018 - journals.lww.com
Long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1
(MALAT1) functions as a crucial regulator of metastasis in lung cancer. The aim of this study …

[HTML][HTML] Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance

J Hou, G Zhang, X Wang, Y Wang, K Wang - Biomarker research, 2023 - Springer
Chemotherapy is one of the most important treatments for cancer therapy. However,
chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy …