Alzheimer's disease (AD) is a predominantly heterogeneous disease with a highly complex
pathobiology. The presence of amyloid-beta (Aβ) depositions and the accumulation of …

As a physiological response to injury in the internal body organs, inflammation is
responsible for removing dangerous stimuli and initiating healing. However, persistent and …

Alzheimer's disease (AD) is the most common neurodegenerative disorder and its
prevalence is increasing. Nowadays, very few drugs effectively reduce AD symptoms and …

Blood-brain barrier disruption occurs in the early stages of Alzheimer's disease. Recent
studies indicate a link between blood-brain barrier dysfunction and cognitive decline and …

Alzheimer's disease (AD) is the most common neurodegenerative disorder that affects the
elderly. The increase of lifeexpectancy is transforming AD into a major health-care problem …

Compelling evidence from basic molecular biology has demonstrated the dual roles of
microglia in the pathogenesis of Alzheimer's disease (AD). On one hand, microglia are …

Neuroinflammation is instigated by the misfiring of immune cells in the central nervous
system (CNS) involving microglia and astrocytes as key cell-types. Neuroinflammation is a …

Neuroinflammation has been observed in association with neurodegenerative diseases
including Alzheimer's disease (AD). In particular, a positive correlation has been …

Neurological degeneration after neuroinflammation, such as that resulting from Alzheimer's
disease (AD), stroke, multiple sclerosis (MS), and post-traumatic brain injury (TBI), is …

Alzheimer's disease (AD) is a multifactorial disease with a heterogeneous etiology. The
pathology of Alzheimer's disease is characterized by amyloid-beta and …