[HTML][HTML] The potential role of cytokines and growth factors in the pathogenesis of Alzheimer's disease
G Ogunmokun, S Dewanjee, P Chakraborty… - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most prominent neurodegenerative diseases, which
impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal …
impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal …
[HTML][HTML] Blood-brain barrier dysfunction and Alzheimer's disease: associations, pathogenic mechanisms, and therapeutic potential
Y Chen, Y He, J Han, W Wei, F Chen - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is a common neurodegenerative disorder characterized by the
accumulation of amyloid-beta (Aβ), hyperphosphorylation of tau, and neuroinflammation in …
accumulation of amyloid-beta (Aβ), hyperphosphorylation of tau, and neuroinflammation in …
[HTML][HTML] Glutamate and GABA in microglia-neuron cross-talk in Alzheimer's disease
GA Czapski, JB Strosznajder - International Journal of Molecular Sciences, 2021 - mdpi.com
The physiological balance between excitation and inhibition in the brain is significantly
affected in Alzheimer's disease (AD). Several neuroactive compounds and their signaling …
affected in Alzheimer's disease (AD). Several neuroactive compounds and their signaling …
[HTML][HTML] Discerning the role of blood brain barrier dysfunction in Alzheimer's disease
QQ Tao, RR Lin, YH Chen, ZY Wu - Aging and Disease, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common form of neurodegenerative disease. The
predominant characteristics of AD are the accumulation of amyloid-β (Aβ) and …
predominant characteristics of AD are the accumulation of amyloid-β (Aβ) and …
Interactions between glial cells and the blood-brain barrier and their role in Alzheimer's disease
M Zhao, XF Jiang, HQ Zhang, JH Sun, H Pei… - Ageing research …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), which is an irreversible neurodegenerative disorder
characterized by senile plaques and neurofibrillary tangles, is the most common form of …
characterized by senile plaques and neurofibrillary tangles, is the most common form of …
[HTML][HTML] The neurovascular unit dysfunction in Alzheimer's disease
LO Soto-Rojas, M Pacheco-Herrero… - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide.
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Revealing the mechanisms of blood–brain barrier in chronic neurodegenerative disease: an opportunity for therapeutic intervention
S Yu, X Chen, T Yang, J Cheng, E Liu… - Reviews in the …, 2024 - degruyter.com
The brain microenvironment is tightly regulated, and the blood–brain barrier (BBB) plays a
pivotal role in maintaining the homeostasis of the central nervous system. It effectively …
pivotal role in maintaining the homeostasis of the central nervous system. It effectively …
[HTML][HTML] Peripheral pathways to neurovascular unit dysfunction, cognitive impairment, and Alzheimer's Disease
AR Nelson - Frontiers in aging neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common form of dementia. It was first described more
than a century ago, and scientists are acquiring new data and learning novel information …
than a century ago, and scientists are acquiring new data and learning novel information …
[HTML][HTML] Proteomic alterations in the brain and blood–brain barrier during brain Aβ accumulation in an APP knock-in mouse model of Alzheimer's disease
Background Blood–brain barrier (BBB) dysfunction is supposed to be an early event in the
development of Alzheimer's disease (AD). This study aimed to investigate the relationship …
development of Alzheimer's disease (AD). This study aimed to investigate the relationship …
[HTML][HTML] Microglia in the neuroinflammatory pathogenesis of Alzheimer's disease and related therapeutic targets
Y Cai, J Liu, B Wang, M Sun, H Yang - Frontiers in immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease worldwide,
characterized by progressive neuron degeneration or loss due to excessive accumulation of …
characterized by progressive neuron degeneration or loss due to excessive accumulation of …