Background: In Alzheimer's disease (AD) neuronal degeneration is associated with gliosis
and infiltration of peripheral blood mononuclear cells (PBMCs), which participate in …

Alzheimer's Disease (AD) is one of the most devastating age-related disorder causing
significant social and economic burden worldwide. It affects the cognitive and social …

Alzheimer's disease (AD) is defined as a severe chronic degenerative neurological disease
in human. The pathogenic mechanism of AD has been convincingly elucidated by the …

• Introduction• Innate immune response in the AD brain‐Microglia‐Astrocyte• Glial cells
mediate the peripheral immune response in AD‐Glial cell interaction with endothelial cells …

Astrocytes, which are five-fold more numerous than neurons in the central nervous system
(CNS), are traditionally viewed to provide simple structural and nutritional supports for …

Amyloid-β (Aβ) pathology is known to promote chronic inflammatory responses in the brain.
It was thought previously that Aβ is only associated with Alzheimer's disease and Down …

The blood-brain barrier (BBB) is the multicellular interface located between the peripheral
circulation and the brain parenchyma. BBB dysfunction is reported in many CNS diseases …

Alzheimer's disease (AD) is a complex degenerative disease of the central nervous system
that is clinically characterized by a progressive decline in memory and cognitive function …

Alzheimer's disease (AD) is the most common form of dementia, affecting more than 50
million people worldwide with an estimated increase to 139 million people by 2050. The …

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
formation of intracellular neurofibrillary tangles (NFTs) and extracellular amyloid plaques …