[HTML][HTML] Risk Factors for Alzheimer's Disease

I Moreno-Gonzalez, R Morales… - Frontiers in Aging …, 2020 - frontiersin.org
Late-onset sporadic Alzheimer's disease (AD) is a multifactorial disease in which several
risk factors contribute to the onset and disease progression. Risk factors for AD include …

[HTML][HTML] Common signaling pathways involved in Alzheimer's disease and stroke: Two Faces of the Same Coin

TK Das, BP Ganesh… - Journal of Alzheimer's …, 2023 - content.iospress.com
Alzheimer's disease (AD) and stroke are two interrelated neurodegenerative disorders
which are the leading cause of death and affect the neurons in the brain and central nervous …

[HTML][HTML] Microglia and Alzheimer's disease

S Merighi, M Nigro, A Travagli, S Gessi - International Journal of …, 2022 - mdpi.com
There is a huge need for novel therapeutic and preventative approaches to Alzheimer's
disease (AD) and neuroinflammation seems to be one of the most fascinating solutions. The …

Neuroinflammation, Microglia and Implications for Anti‐Inflammatory Treatment in Alzheimer′ s Disease

DL Krause, N Müller - International journal of Alzheimer's …, 2010 - Wiley Online Library
Neuroinflammation has been implicated in the pathology of Alzheimer′ s disease (AD) for
decades. Still it has not been fully understood when and how inflammation arises in the …

Peripheral inflammatory biomarkers of Alzheimer's disease: the role of platelets

T Casoli, G Di Stefano, M Balietti, M Solazzi, B Giorgetti… - Biogerontology, 2010 - Springer
Alzheimer's disease is an age-dependent neurodegenerative disorder characterized by loss
of neurons, synaptic degeneration, senile plaques and neurofibrillary tangles. Besides these …

[HTML][HTML] Blood-based biomarkers of neuroinflammation in Alzheimer's disease: a central role for periphery?

F Angiulli, E Conti, CP Zoia, F Da Re, I Appollonio… - Diagnostics, 2021 - mdpi.com
Neuroinflammation represents a central feature in the development of Alzheimer's disease
(AD). The resident innate immune cells of the brain are the principal players in …

[HTML][HTML] HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in …

BW Festoff, RK Sajja, P van Dreden… - Journal of …, 2016 - Springer
Background The blood-brain barrier (BBB) dysfunction represents an early feature of
Alzheimer's disease (AD) that precedes the hallmarks of amyloid beta (amyloid β) plaque …

[HTML][HTML] Novel Development and Prospects in Pathogenesis, Diagnosis, and Therapy of Alzheimer's Disease

Z Teng - Journal of Alzheimer's Disease Reports, 2024 - content.iospress.com
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease with cognitive
decline and behavioral dysfunction. AD will become a global public health concern due to its …

Understanding the role of systemic inflammation in Alzheimer's disease

KA Walker, BN Ficek, R Westbrook - ACS chemical neuroscience, 2019 - ACS Publications
Human and animal studies suggest that inflammation occurring outside the central nervous
system (systemic inflammation) may play a key role in promoting neurodegeneration …

[HTML][HTML] Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease

WY Wang, MS Tan, JT Yu, L Tan - Annals of translational medicine, 2015 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain, which is
characterized by the formation of extracellular amyloid plaques (or senile plaques) and …