The essential trace element selenium is also toxic at low doses. Since supplementation of
selenium is discussed as cancer prophylaxis, we investigated whether or not bioavailable …

Previous studies in animals and humans have shown that selenium compounds can prevent
cancer development. In this work we studied the tumor preventive effect of selenium …

Although the earlier literature regarding selenium stressed its toxicity, especially its role in
carcinogenesis, there is an increasingly held view that selenium is an essential trace …

The present study was designed to investigate whether there is any correlation between the
anticarcinogenic efficacy of selenium (Se) compounds and tissue Se retention under high …

HERE IS INCREASING evidence in the literature that selenium supplementation can protect
labora-T tory animals against preneoplastic lesion development or tumorigenesis induced …

Selenium is a cellular growth inhibitor in many mammary tumor cells. To comprehend the
mechanism for the selenium-induced cell death, we examined the effects of sodium selenite …

Methylated selenides are prominent metabolites at the dietary levels used for obtaining
anticarcinogenic effects with selenium. The present study reports the chemopreventive …

Selenium has been reported to affect glutathione (GSH) concentrations in short-term animal-
feeding experiments. Given the central role that this tripeptide plays in maintaining cellular …

Abstract Sodium selenite (Na 2 SeO 3) was administered at 2.0 µg selenium (Se) to Swiss
ICR mice six times over a 9-day period by intraperitoneal (ip) injection or by gastric gavage …

The development of new compounds with greater cancer inhibitory activity and that are well
tolerated continues to be a priority in chemoprevention research involving selenium. One …