Selenium is a necessary dietary constituent of at least 25 human selenoproteins and
enzymes all containing selenocysteine. In excessive amounts, all selenium compounds …

Since high levels of selenium are used as cancer chemopreventive agents in animals and
humans, a better understanding of the metabolism of subtoxic levels is desirable. Absorption …

A number of cytotoxicity assays are currently available, each of them using specific
approach to detect different aspects of cell viability, such as cell integrity, proliferation and …

The data in this report clearly indicate that the form (structure) in which selenium is used is
the most critical determinant of success in future clinical trials. Synthetic organoselenium …

Selenium supplementation has been shown for many years to work as an anticarcinogenic
agent both in epidemiology and in in vitro studies. Selenium supplementation has recently …

Selenium is effective in reducing cancer incidence in animal models, and epidemiologic
data, as well as supplementation trials, have indicated that selenium is likely to be effective …

Cells cultivated under standard conditions were highly deficient in tocopherol, selenium, and
glutathione peroxidase (GPx) activities. We investigated whether and to what extent the …

The experiments reported herein examined the inhibitory role of selenium in chemical
carcinogen-induced mouse mammary tumorigenesis. The results from four different …

The advance in the area of synthesis and reactivity of organoselenium, as well as the
discovery that selenium was the cause of severe intoxication episodes of livestock in the …

A major research goal of our laboratories is the development of new organoselenium cancer
chemopreventive agents with less toxicity compared to some of the historical selenium …