Elevated levels of interleukin (IL)‐18 have been reported in a number of allergic diseases.
We recently reported that IL‐18 in the blood and IL‐18Rα mRNA in the oesophagus are …

Several studies have shown that interleukin (IL)‐13 is induced in the esophageal biopsies of
eosinophilic esophagitis (EoE) patients and promotes esophageal eosinophilia in mice …

Eosinophil infiltration into the esophagus occurs in a wide range of diseases; however, the
underlying pathophysiological mechanisms involved are largely unknown. We now report …

BACKGROUND & AIMS: Quantitative microarray analyses have shown increased
expression of interleukin-15 (IL-15) messenger RNA in the esophagus of patients with …

Eosinophilic esophagitis (EE) is an emerging disease associated with both food and
respiratory allergy characterized by extensive esophageal tissue remodeling and abnormal …

Background: IL-13 induces several characteristic features of asthma, including airway
eosinophilia, airway hyperresponsiveness, and mucus overproduction; however, the …

BACKGROUND & AIMS:: Eosinophil infiltration into the esophagus occurs in a wide range of
diseases; however, the underlying pathophysiologic mechanisms involved are largely …

Baseline eosinophils reside in the gastrointestinal tract; however, in several allergic
disorders, excessive eosinophils accumulate in the blood as well in the tissues. Recently …

IL-18 is induced in food allergy and EoE is food allergen-induced disease. Therefore, we
tested the hypothesis whether IL-18 is involved in food allergen-induced EoE pathogenesis …

Abstract Interleukin‐18 (IL‐18), a proinflammatory cytokine, leads to IFN‐γ production by NK
or T cells, induces Th1 differentiation and suppresses IgE synthesis by B cells when acting …