Optimization and formulation of fucoxanthin-loaded microsphere (F-LM) using response surface methodology (RSM) and analysis of its fucoxanthin release profile

I Jaswir, D Noviendri, M Taher, F Mohamed… - Molecules, 2019 - mdpi.com
Fucoxanthin has interesting anticancer activity, but is insoluble in water, hindering its use as
a drug. Microencapsulation is used as a technique for improving drug delivery. This study …

Fabrication of fucoxanthin-loaded microsphere (F-LM) by two steps double-emulsion solvent evaporation method and characterization of fucoxanthin before and after …

D Noviendri, I Jaswir, M Taher, F Mohamed… - Journal of Oleo …, 2016 - jstage.jst.go.jp
Microencapsulation is a promising approach in drug delivery to protect the drug from
degradation and allow controlled release of the drug in the body. Fucoxanthin-loaded …

Investigation of the optimal fabrication of a single-carrier encapsulated fucoxanthin based on colloidal nanoparticles

X Zhang, M Fan, Y Yuan, J Dong, H Yin, Y He… - Journal of Industrial and …, 2022 - Elsevier
Fucoxanthin (FX) is a carotenoid with antioxidant, anti-obesity, anti-diabetic, anti-cancer and
anti-bacterial activities. It is poorly water soluble and highly sensitive to light, heat and the …

Fucoxanthin activities motivate its nano/micro-encapsulation for food or nutraceutical application: a review

C Wang, X Chen, Y Nakamura, C Yu, H Qi - Food & Function, 2020 - pubs.rsc.org
Fucoxanthin is a xanthophyll carotenoid abundant in marine brown algae. The potential
therapeutic effects of fucoxanthin on tumor intervention have been well documented, which …

Synthesis and physicochemical characterization of rhamnolipid fabricated fucoxanthin loaded bovine serum albumin nanoparticles supported by simulation studies

J Jaiswal, AK Srivastav, R Patel… - Journal of the Science of …, 2022 - Wiley Online Library
BACKGROUND Fucoxanthin is a hydrophobic carotenoid with many beneficial biological
activities. However, due to low aqueous solubility their clinical efficacy is limited thus leading …

Stability and biological activity enhancement of fucoxanthin through encapsulation in alginate/chitosan nanoparticles

FN Sorasitthiyanukarn, C Muangnoi… - International Journal of …, 2024 - Elsevier
A response surface methodology based on the Box-Behnken design was employed to
develop fucoxanthin (FX) delivery nanocarrier from alginate (ALG) and chitosan (CS). The …

Fucoxanthin loaded in palm stearin-and cholesterol-based solid lipid nanoparticle-microcapsules, with improved stability and bioavailability in vivo

Y Chen, N He, T Yang, S Cai, Y Zhang, J Lin, M Huang… - Marine drugs, 2022 - mdpi.com
Fucoxanthin (FX) is a marine carotenoid that has proven to be a promising marine drug due
to the multiple bioactivities it possesses. However, the instability and poor bioavailability of …

The stability and bioaccessibility of fucoxanthin in spray-dried microcapsules based on various biopolymers

X Sun, Y Xu, L Zhao, H Yan, S Wang, D Wang - RSC advances, 2018 - pubs.rsc.org
Fucoxanthin is a major marine carotenoid with many biological activities. It is well known that
fucoxanthin is unstable to heat and acid due to its polyunsaturated structure. Another defect …

Amazonia products in novel lipid nanoparticles for fucoxanthin encapsulation

LM Cordenonsi, A Santer, RM Sponchiado… - AAPS …, 2020 - Springer
Lipid nanoparticles (LNs) are traditional systems able to effectively increase skin hydration.
However, due to its reduced viscosity, LNs suspensions are less attractive for skin …

Preparation of fucoxanthin nanoemulsion stabilized by natural emulsifiers: Fucoidan, sodium caseinate, and gum arabic

N Oliyaei, M Moosavi-Nasab, N Tanideh - Molecules, 2022 - mdpi.com
This study was proposed to investigate the possibility of O/W nanoemulsion stabilization via
natural emulsifiers as a delivery system for fucoxanthin. Nanoemulsions were prepared …