[HTML][HTML] Immunologic correlates of the abscopal effect in a patient with melanoma

MA Postow, MK Callahan, CA Barker… - … England Journal of …, 2012 - Mass Medical Soc
The abscopal effect is a phenomenon in which local radiotherapy is associated with the
regression of metastatic cancer at a distance from the irradiated site. The abscopal effect …

The abscopal effect associated with a systemic anti-melanoma immune response

EF Stamell, JD Wolchok, S Gnjatic, NY Lee… - International Journal of …, 2013 - Elsevier
The clearance of nonirradiated tumors after localized radiation therapy is known as the
abscopal effect. Activation of an antitumor immune response has been proposed as a …

[HTML][HTML] Radiation therapy and the abscopal effect: a concept comes of age

J Ng, T Dai - Annals of translational medicine, 2016 - ncbi.nlm.nih.gov
The concept of utilizing localized radiation therapy to elicit out-of-target tumor responses—
the abscopal effect—was proposed over 50 years ago (1, 2). Over the past decades, the …

[HTML][HTML] Abscopal effect of radiotherapy combined with immune checkpoint inhibitors

Y Liu, Y Dong, L Kong, F Shi, H Zhu, J Yu - Journal of hematology & …, 2018 - Springer
Radiotherapy (RT) is used routinely as a standard treatment for more than 50% of patients
with malignant tumors. The abscopal effect induced by local RT, which is considered as a …

[HTML][HTML] The abscopal effect: a review of pre-clinical and clinical advances

JR Janopaul-Naylor, Y Shen, DC Qian… - International journal of …, 2021 - mdpi.com
Radiotherapy has been used for more than a hundred years to cure or locally control tumors.
Regression of tumors outside of the irradiated field was occasionally observed and is known …

[HTML][HTML] Abscopal effect, from myth to reality: from radiation oncologists' perspective

MT Yilmaz, A Elmali, G Yazici - Cureus, 2019 - ncbi.nlm.nih.gov
The abscopal effect is mediated by a systemic anti-tumor immune response and reflects the
regression of non-irradiated metastatic lesions at a distance from the primary site of …

Analysis of the abscopal effect with anti-PD1 therapy in patients with metastatic solid tumors

JR Gomes, RA Schmerling, CK Haddad… - Journal of …, 2016 - journals.lww.com
Abscopal effect is a rare phenomenon characterized by tumor regression of untreated
metastatic lesions after a local therapy (eg, radiotherapy). We studied the probability of …

Abscopal effects of radiotherapy on advanced melanoma patients who progressed after ipilimumab immunotherapy

AM Grimaldi, E Simeone, D Giannarelli, P Muto… - …, 2014 - Taylor & Francis
Cancer radiotherapy (RT) may induce what is referred to as the “abscopal effect,” a
regression of non-irradiated metastatic lesions distant from the primary tumor site directly …

[HTML][HTML] A review of the abscopal effect in the era of immunotherapy

E Nabrinsky, J Macklis, J Bitran - Cureus, 2022 - ncbi.nlm.nih.gov
The abscopal effect is a systemic immune response mediated by the effects of radiation on
the immune system. This effect has been observed in a number of cancer types in addition to …

[PDF][PDF] Abscopal effect in a patient with melanoma

SM Hiniker, DS Chen, SJ Knox - N Engl J Med, 2012 - researchgate.net
To the Editor: Postow et al.(March 8 issue) 1 report an abscopal effect in a patient with
melanoma treated with ipilimumab and radiotherapy, with a response in nonirradiated …