Aggressive pituitary adenomas—diagnosis and emerging treatments

A Di Ieva, F Rotondo, LV Syro, MD Cusimano… - Nature Reviews …, 2014 - nature.com
The WHO categorizes pituitary tumours as typical adenomas, atypical adenomas and
pituitary carcinomas, with typical adenomas constituting the major class. However, the WHO …

Aggressive pituitary tumors

E Chatzellis, KI Alexandraki, II Androulakis… - …, 2015 - karger.com
Pituitary adenomas are common intracranial tumors that are mainly considered as benign.
Rarely, these tumors can exhibit an aggressive behavior, characterized by gross invasion of …

Definition and diagnosis of aggressive pituitary tumors

L Kasuki, G Raverot - Reviews in Endocrine and Metabolic Disorders, 2020 - Springer
Pituitary adenomas are considered benign tumors, but approximately 10% of them can have
an aggressive behavior and more rarely (0.2%) can present metastasis, being classified as …

Management of aggressive pituitary adenomas and pituitary carcinomas

A Heaney - Journal of neuro-oncology, 2014 - Springer
Pituitary tumors are benign but not uncommonly invade locally into adjacent tissues such as
the cavernous sinus and dura. Some of these invasive tumors exhibit varying degrees of …

The epidemiology of aggressive pituitary tumors (and its challenges)

OM Dekkers, N Karavitaki, AM Pereira - Reviews in Endocrine and …, 2020 - Springer
Pituitary tumors are not rare if prevalence rates from autopsy or radiological series are
considered; approximately 0.5% of all pituitary adenomas will come to medical attention …

Aggressive pituitary tumours and carcinomas: two sides of the same coin?

J Trouillas, P Burman, A McCormack… - European Journal of …, 2018 - academic.oup.com
Abstract The European Society of Endocrinology (ESE) survey reported on the largest cohort
of 125 aggressive pituitary tumours (APT) and 40 pituitary carcinomas (PC). Whilst the …

Progress in the diagnosis and classification of pituitary adenomas

LV Syro, F Rotondo, A Ramirez, A Di Ieva… - Frontiers in …, 2015 - frontiersin.org
Pituitary adenomas are common neoplasms. Their classification is based upon size,
invasion of adjacent structures, sporadic or familial cases, biochemical activity, clinical …

Are aggressive pituitary tumors and carcinomas two sides of the same coin? Pathologists reply to clinician's questions

J Trouillas, ML Jaffrain-Rea, A Vasiljevic… - Reviews in Endocrine …, 2020 - Springer
Pituitary adenohypophyseal tumors are considered as benign and termed “adenomas”.
However, many tumors are invasive and a proportion of these exhibit an “aggressive …

New WHO classification of pituitary adenomas: assessment of pituitary transcription factors and the prognostic histological factors

H Nishioka, N Inoshita - Brain tumor pathology, 2018 - Springer
WHO classification of pituitary adenomas was revised in 2017. The two major and significant
changes are discussed.(1) The new classification focuses on adenohypophysial-cell lineage …

Management of endocrine disease: clinicopathological classification and molecular markers of pituitary tumours for personalized therapeutic strategies

G Raverot, E Jouanneau… - European journal of …, 2014 - academic.oup.com
Pituitary tumours, the most frequent intracranial tumour, are historically considered benign.
However, various pieces of clinical evidence and recent advances in pathological and …