G-quadruplex structures are among the most interesting and best-characterized DNA folding
motifs.[1] DNA sequences that can form stable G-quadruplexes in vitro have been implicated …

Syntheses and telomeric G-quadruplex− DNA binding properties of novel bisquinolinium
compounds are reported. This series exhibits remarkable efficiency both in terms of …

Organic small molecules that can recognize and bind to G-quadruplex and i-Motif nucleic
acids have great potential as selective drugs or as tools in drug target discovery programs …

A G-quadruplex is a four-stranded DNA structure featuring stacked guanine tetrads, G-
quartets. Formation of a G-quadruplex in telomere DNA can inhibit telomerase activity; …

A G-quadruplex (quadruplex) is a nucleic acid secondary structure adopted by guanine-rich
sequences and is considered to be relevant to various pharmacological and biological …

Two symmetrical cyanine dyes based on benzothiazole heterocycles and a trimethine
bridge were found to bind to a parallel-stranded DNA guanine quadruplex based on the …

A new class of quadruplex nucleobases, derived from 3‐deazaguanine, has been designed
for various applications as smart quadruplex ligands as well as quadruplex‐based …

A series of bisaryldiketene derivatives were designed and synthesized as a new class of
specific G-quadruplex ligands. The ligand–quadruplex interactions were further evaluated …

Thiazole orange is a commonly used cyanine dye for binding to nucleic acids. Recently, it
has been used for the detection of G-quadruplexes. However, thiazole orange is non …

G-quadruplex DNA-specific ligands were generated using a combinatorial selection of
tetrapeptides which were then conjugated to a hemicyanine scaffold. The heterocycle …