Many cardiovascular events are clinical manifestations of underlying atherosclerotic
disease. The progression of atherosclerosis, traditionally measured by angiography, is …

Atherosclerosis imaging has taken on increasing importance in the understanding of the
natural history of coronary artery disease and the processes leading to luminal narrowing …

Clinicians have long used the size of the lumen and the angiogram as a predictor of
coronary events. However, cardiovascular disease is not a disease of the lumen but a …

The incremental value of intravascular ultrasound (IVUS), compared with angiographic
analysis of coronary atherosclerosis, originates principally from 2 key features—its …

Coronary heart disease remains a leading cause of morbidity and mortality. Surrogate
imaging endpoints may allow smaller sample sizes and shorter study durations to expedite …

Angiography has major limitations in its ability to assess coronary disease. Intravascular
ultrasound (IVUS) offers unique capabilities to assess coronary atherosclerotic burden. The …

Intravascular ultrasound (IVUS) is a valuable adjunct to angiography, providing new insights
in the diagnosis of and therapy for coronary disease. Angiography depicts only a 2D …

Are progressive changes in intravascular ultrasound (IVUS)-derived indexes of plaque size
sufficiently predictive of in-trial or future cardiovascular event risk that IVUS can serve as an …

The introduction of catheter-based intravascular ultrasound (IVUS) imaging in peripheral35
and coronary10, 19 vessels has revolutionized understanding of atherosclerotic artery …

Intravascular ultrasound (IVUS) provides valuable information on the coronary vascular
lumen and wall and has been an important tool in the cardiac catheterization laboratory for …