Apixaban for extended treatment of venous thromboembolism
Background Apixaban, an oral factor Xa inhibitor that can be administered in a simple, fixed-
dose regimen, may be an option for the extended treatment of venous thromboembolism …
dose regimen, may be an option for the extended treatment of venous thromboembolism …
Oral apixaban for the treatment of acute venous thromboembolism
Background Apixaban, an oral factor Xa inhibitor administered in fixed doses, may simplify
the treatment of venous thromboembolism. Methods In this randomized, double-blind study …
the treatment of venous thromboembolism. Methods In this randomized, double-blind study …
Effectiveness and safety of apixaban versus rivaroxaban for prevention of recurrent venous thromboembolism and adverse bleeding events in patients with venous …
Background Apixaban and rivaroxaban, both direct-acting oral anticoagulants, are being
increasingly used in routine clinical practice because of their fixed dosing and favourable …
increasingly used in routine clinical practice because of their fixed dosing and favourable …
Quantification of apixaban's therapeutic utility in prevention of venous thromboembolism: selection of phase III trial dose
TA Leil, Y Feng, L Zhang, A Paccaly… - CliniCal …, 2010 - Wiley Online Library
A model‐based approach was used to integrate data from a phase II study in order to
provide a quantitative rationale for selecting the apixaban dosage regimen for a phase III …
provide a quantitative rationale for selecting the apixaban dosage regimen for a phase III …
Efficacy and safety of the oral direct factor Xa inhibitor apixaban for symptomatic deep vein thrombosis. The Botticelli DVT dose‐ranging study
Botticelli investigators, the writing … - … of Thrombosis and …, 2008 - Wiley Online Library
Background: Apixaban, an oral potent reversible direct inhibitor of activated factor X, has
shown promise in the prevention of venous thromboembolism following major orthopedic …
shown promise in the prevention of venous thromboembolism following major orthopedic …
Apixaban for the treatment of Japanese subjects with acute venous thromboembolism (AMPLIFY-J Study)
M Nakamura, M Nishikawa, I Komuro, I Kitajima… - Circulation …, 2015 - jstage.jst.go.jp
Background: Anticoagulation is recommended as standard of care for venous
thromboembolism (VTE)(pulmonary embolism [PE]/deep vein thrombosis [DVT]), for which …
thromboembolism (VTE)(pulmonary embolism [PE]/deep vein thrombosis [DVT]), for which …
Risk for recurrent venous thromboembolism and bleeding with apixaban compared with rivaroxaban: an analysis of real-world data
GK Dawwas, CE Leonard, JD Lewis… - Annals of internal …, 2022 - acpjournals.org
Background: Apixaban and rivaroxaban are replacing vitamin K antagonists for the
treatment of venous thromboembolism (VTE) in adults; however, head-to-head comparisons …
treatment of venous thromboembolism (VTE) in adults; however, head-to-head comparisons …
Rivaroxaban or aspirin for extended treatment of venous thromboembolism
JI Weitz, AWA Lensing, MH Prins… - … England Journal of …, 2017 - Mass Medical Soc
Background Although many patients with venous thromboembolism require extended
treatment, it is uncertain whether it is better to use full-or lower-intensity anticoagulation …
treatment, it is uncertain whether it is better to use full-or lower-intensity anticoagulation …
Apixaban, an oral direct Factor Xa inhibitor: awaiting the verdict
J Carreiro, J Ansell - Expert Opinion on Investigational Drugs, 2008 - Taylor & Francis
For the last half-century, despite its many limitations warfarin has been the mainstay of
treatment for patients with venous and arterial thromboembolic disease. During the past …
treatment for patients with venous and arterial thromboembolic disease. During the past …
[HTML][HTML] Apixaban: a clinical pharmacokinetic and pharmacodynamic review
W Byon, S Garonzik, RA Boyd, CE Frost - Clinical pharmacokinetics, 2019 - Springer
Apixaban is an oral, direct factor Xa inhibitor that inhibits both free and clot-bound factor Xa,
and has been approved for clinical use in several thromboembolic disorders, including …
and has been approved for clinical use in several thromboembolic disorders, including …
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