Rivastigmine-loaded PLGA and PBCA nanoparticles: preparation, optimization, characterization, in vitro and pharmacodynamic studies
Sustained release nanoparticulate formulations of Rivastigmine tartrate (RT) were prepared,
optimized (using factorial design) and characterized using the biodegradable polymers …
optimized (using factorial design) and characterized using the biodegradable polymers …
Optimization of brain targeted chitosan nanoparticles of Rivastigmine for improved efficacy and safety
The study aims at formulation and optimization brain targeted nanoparticles (NP) of
Rivastigmine (RT) to improve its therapeutic potential and to verify its safety profile. The NP …
Rivastigmine (RT) to improve its therapeutic potential and to verify its safety profile. The NP …
Development and evaluation of rivastigmine loaded chitosan nanoparticles for brain targeting
The rivastigmine (RHT) loaded chitosan nanoparticles (CS-RHT NPs) were prepared by
ionic gelation method to improve the bioavailability and enhance the uptake of RHT to the …
ionic gelation method to improve the bioavailability and enhance the uptake of RHT to the …
Estradiol loaded PLGA nanoparticles for oral administration: effect of polymer molecular weight and copolymer composition on release behavior in vitro and in vivo
G Mittal, DK Sahana, V Bhardwaj… - Journal of controlled …, 2007 - Elsevier
The present investigation was aimed at optimization of estradiol loaded PLGA
nanoparticulate formulations resulting in improved oral bioavailability and sustained release …
nanoparticulate formulations resulting in improved oral bioavailability and sustained release …
Poly (n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
B Wilson, MK Samanta, K Santhi, KPS Kumar… - Brain research, 2008 - Elsevier
Alzheimer's disease is a progressive and fatal neurodegenerative disorder manifested by
cognitive and memory deterioration, progressive impairment of activities of daily living, and a …
cognitive and memory deterioration, progressive impairment of activities of daily living, and a …
Potential therapeutic effect of nanobased formulation of rivastigmine on rat model of Alzheimer's disease
MF Ismail, AN ElMeshad… - International journal of …, 2013 - Taylor & Francis
Background To sustain the effect of rivastigmine, a hydrophilic cholinesterase inhibitor,
nanobased formulations were prepared. The efficacy of the prepared rivastigmine liposomes …
nanobased formulations were prepared. The efficacy of the prepared rivastigmine liposomes …
PLGA nanoparticle formulations of risperidone: preparation and neuropharmacological evaluation
The aim of this work was to develop extended-release poly (d, l-lactide-co-glycolide)(PLGA)
nanoparticles of risperidone and thermal-responsive in situ gel containing risperidone …
nanoparticles of risperidone and thermal-responsive in situ gel containing risperidone …
Preparation, characterization, in vivo biodistribution and pharmacokinetic studies of donepezil-loaded PLGA nanoparticles for brain targeting
Objective: Alzheimer's disease (AD) is a progressive neurodegenerative disorder
manifested by cognitive, memory deterioration and variety of neuropsychiatric symptoms …
manifested by cognitive, memory deterioration and variety of neuropsychiatric symptoms …
Surface modified PLGA nanoparticles for brain targeting of Bacoside-A
The present paper focuses on the development and in vitro/in vivo characterization of
nanoparticles composed of poly-(D, L)-Lactide-co-Glycolide (PLGA) loading Bacoside-A, as …
nanoparticles composed of poly-(D, L)-Lactide-co-Glycolide (PLGA) loading Bacoside-A, as …
Boosted memory and improved brain bioavailability of rivastigmine: targeting effort to the brain using covalently tethered lower generation PAMAM dendrimers with …
Currently, there is no treatment strategy which can reverse the process of neuro-
degeneration in progression of Alzheimer's disease (AD). Practically, it is desired to achieve …
degeneration in progression of Alzheimer's disease (AD). Practically, it is desired to achieve …