Summary Type IV CRISPR-Cas systems, which are primarily found on plasmids and exhibit
a strong plasmid-targeting preference, are the only one of the six known CRISPR-Cas types …

Bacteria and archaea possess a range of defense mechanisms to combat plasmids and viral
infections. Unique among these are the CRISPR-Cas (clustered regularly interspaced short …

Clustered regularly interspaced short palindromic repeats interference (CRISPRi) is an
emerging technology for artificial gene regulation. Type II CRISPR-Cas endonuclease Cas9 …

CRISPR–Cas12f nucleases are currently one of the smallest genome editors, exhibiting
advantages for efficient delivery via cargo-size-limited adeno-associated virus delivery …

Over the last decade, research on distinct types of CRISPR systems has revealed many
structural and functional variations. Recently, several novel types of single-polypeptide …

Class 2 CRISPR–Cas systems, such as Cas9 and Cas12, have been widely used to target
DNA sequences in eukaryotic genomes. However, class 1 CRISPR–Cas systems, which …

CRISPR (clustered regularly interspaced short palindromic repeat) systems have been
broadly adopted for basic science, biotechnology, and gene and cell therapy. In some …

CRISPR-Cas systems are a diverse family of RNA-protein complexes in bacteria that target
foreign DNA sequences for cleavage. Derivatives of these complexes have been …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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CRISPR-Cas systems enable microbial adaptive immunity and provide eukaryotic genome
editing tools. These tools employ a single effector enzyme of type II or V CRISPR to generate …