Structure-based prediction of binding peptides to MHC class I molecules: application to a broad range of MHC alleles
Specific binding of antigenic peptides to major histocompatibility complex (MHC) class I
molecules is a prerequisite for their recognition by cytotoxic T-cells. Prediction of MHC …
molecules is a prerequisite for their recognition by cytotoxic T-cells. Prediction of MHC …
A structure-based algorithm to predict potential binding peptides to MHC molecules with hydrophobic binding pockets
Binding of peptides to MHC class I molecules is a prerequisite for their recognition by
cytotoxic T cells. Consequently, identification of peptides that will bind to a given MHC …
cytotoxic T cells. Consequently, identification of peptides that will bind to a given MHC …
Ab initio prediction of peptide‐MHC binding geometry for diverse class I MHC allotypes
AJ Bordner, R Abagyan - Proteins: Structure, Function, and …, 2006 - Wiley Online Library
Since determining the crystallographic structure of all peptide‐MHC complexes is infeasible,
an accurate prediction of the conformation is a critical computational problem. These models …
an accurate prediction of the conformation is a critical computational problem. These models …
An automated prediction of MHC class I-binding peptides based on positional scanning with peptide libraries
K Udaka, KH Wiesmüller, S Kienle, G Jung… - Immunogenetics, 2000 - Springer
Specificities of three mouse major histocompatibility complex (MHC) class I molecules, K b,
D b, and L d, were analyzed by positional scanning using combinatorial peptide libraries …
D b, and L d, were analyzed by positional scanning using combinatorial peptide libraries …
A structure-based approach for prediction of MHC-binding peptides
Y Altuvia, H Margalit - Methods, 2004 - Elsevier
Identification of immunodominant peptides is the first step in the rational design of peptide
vaccines aimed at T-cell immunity. The advances in sequencing techniques and the …
vaccines aimed at T-cell immunity. The advances in sequencing techniques and the …
Structural prediction of peptides binding to MHC class I molecules
HH Bui, AJ Schiewe, H von Grafenstein… - Proteins: Structure …, 2006 - Wiley Online Library
Peptide binding to class I major histocompatibility complex (MHCI) molecules is a key step in
the immune response and the structural details of this interaction are of importance in the …
the immune response and the structural details of this interaction are of importance in the …
Prediction of MHC class I binding peptides using profile motifs
PA Reche, JP Glutting, EL Reinherz - Human immunology, 2002 - Elsevier
Peptides that bind to a given major histocompatibility complex (MHC) molecule share
sequence similarity. Therefore, a position specific scoring matrix (PSSM) or profile derived …
sequence similarity. Therefore, a position specific scoring matrix (PSSM) or profile derived …
Ranking potential binding peptides to MHC molecules by a computational threading approach
Y Altuvia, O Schueler, H Margalit - Journal of molecular biology, 1995 - Elsevier
In this paper, an approach developed to address the inverse protein folding problem is
applied to prediction of potential binding peptides to a specific major histocompatibility …
applied to prediction of potential binding peptides to a specific major histocompatibility …
A novel predictive technique for the MHC class II peptide-binding interaction
Antigenic peptide is presented to a T-cell receptor through the formation of a stable complex
with a Major Histocompatibility Complex (MHC) molecule. Various predictive algorithms …
with a Major Histocompatibility Complex (MHC) molecule. Various predictive algorithms …
Knowledge-based structure prediction of MHC class I bound peptides: a study of 23 complexes
Background: The binding of T-cell antigenic peptides to MHC molecules is a prerequisite for
their immunogenicity. The ability to identify binding peptides based on the protein sequence …
their immunogenicity. The ability to identify binding peptides based on the protein sequence …