Diacerein protects against glycerol-induced acute kidney injury: modulating oxidative stress, inflammation, apoptosis and necroptosis

RN Abd-Ellatif, II Hegab, MM Atef, MT Sadek… - Chemico-biological …, 2019 - Elsevier
Necroptosis is suggested to have an important role in the pathogenesis of rhabdomyolysis
induced acute kidney injury (AKI). In this study, the renoprotective effect of diacerein on …

Effect of curcumin on glycerol-induced acute kidney injury in rats

J Wu, X Pan, H Fu, Y Zheng, Y Dai, Y Yin, Q Chen… - Scientific reports, 2017 - nature.com
The aim of this study was to investigate the protective role and underlying mechanisms of
curcumin on glycerol-induced acute kidney injury (AKI) in rats. Glycerol (10 ml/kg BW, 50 …

Protective effect of thymol on glycerol-induced acute kidney injury

Q Wang, G Qi, H Zhou, F Cheng, X Yang, X Liu… - Renal failure, 2023 - Taylor & Francis
Acute kidney injury (AKI) is a syndrome characterized by an accelerating decrease in renal
function in a short time. Thymol is one of the main components of thyme species and has a …

Donepezil protects glycerol-induced acute renal failure through the cholinergic anti-inflammatory and nitric oxide pathway in rats

G Sun, J Wang, P Wang, H Ren, Y Yue… - Immunopharmacology …, 2020 - Taylor & Francis
Objectives Inflammation as well as oxygen metabolite play important roles in renal injury
during pathogenesis of rhabdomyolysis induced myoglobinuric acute renal failure (ARF) …

Perspective on rhabdomyolysis-induced acute kidney injury and new treatment options

S Ulusoy, G Ozkan, M Alkanat, S Mungan… - American journal of …, 2013 - karger.com
Aim: The purpose of this study was to assess the role of caspase-dependent apoptosis,
caspase 1, calpain 1, inducible nitric oxide synthase (iNOS) and endothelial nitric oxide …

Rhabdomyolysis-induced acute kidney injury and concomitant apoptosis induction via ROS-mediated ER stress is efficaciously counteracted by epigallocatechin …

SN Chang, M Haroon, DK Dey, SC Kang - The Journal of Nutritional …, 2022 - Elsevier
Rhabdomyolysis induced acute kidney injury (RIAKI) is a life-threatening condition
responsible for approximately 19-58% of AKI cases worldwide. We performed an …

N-acetylcysteine attenuates glycerol-induced acute kidney injury by regulating MAPKs and Bcl-2 family proteins

JH Kim, SS Lee, MH Jung, HD Yeo… - Nephrology Dialysis …, 2010 - academic.oup.com
Background. Rhabdomyolysis-induced acute kidney injury (AKI) accounts for about 10 to
40% of all cases of AKI. It is known that N-acetylcysteine (NAC) is effective in various …

Oleuropein suppresses oxidative, inflammatory, and apoptotic responses following glycerol-induced acute kidney injury in rats

M Yin, N Jiang, L Guo, Z Ni, AY Al-Brakati, MS Othman… - Life sciences, 2019 - Elsevier
Aim Here, we evaluated the possible protective effects of oleuropein, the major phenolic
constituent in virgin olive oil against glycerol-induced acute kidney injury (AKI) in rats. Main …

Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated …

L Al-Kharashi, H Attia, A Alsaffi, T Almasri… - Toxicology and Applied …, 2023 - Elsevier
Acute kidney injury (AKI) is a common complication of rhabdomyolysis (RM), a syndrome
characterized by skeletal muscle damage resulting in renal tubular oxidative stress …

L-Citrulline Protects Against Glycerol-Induced Acute Renal Failure in Rats

Y Liu*, X Fu*, L Gou, S Li, N Lan, Y Zheng, X Yin - Renal failure, 2013 - Taylor & Francis
There is an increasing evidence that oxidative stress plays an important role in the
pathogenesis of rhabdomyolysis-induced acute renal failure (ARF). In this study, protective …