Cardiovascular diseases (CVD) are the result of complex interactions between both
environmental and genetic factors. The current evidence indicates that, unlike the rare and …

Most genome-wide association studies (GWAS) for lipid traits focus on the separate analysis
of lipid traits. Moreover, there are limited GWASs evaluating the genetic variants associated …

Aim Genetic investigation of human plasma lipidome to get insights into lipid-related
disorders beyond traditional lipid measures. Methods and Results We performed a genome …

Accounting for polygenic effects increases the numbers of dyslipidemic individuals who can
be explained genetically, but a substantial proportion of susceptibility remains unexplained …

Although a considerable proportion of serum lipids loci identified in European ancestry
individuals (EA) replicate in African Americans (AA), interethnic differences in the distribution …

Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …

Abnormal blood lipid levels are influenced by genetic and lifestyle/dietary factors. Although
many genetic variants associated with blood lipid traits have been identified in Europeans …

Insights into genetic origin of diseases and related traits could substantially impact strategies
for improving human health. The results of genome-wide association studies (GWAS) are …

Abstract Purpose of Review Plasma triglycerides are routinely measured with a lipid profile,
and elevated plasma triglycerides are commonly encountered in the clinic. The confounded …

Background/Objective In Japanese populations, we performed a replication study of genetic
loci previously identified in European-descent populations as being associated with lipid …