TRPM2: a multifunctional ion channel for calcium signalling
A Sumoza‐Toledo, R Penner - The Journal of physiology, 2011 - Wiley Online Library
The transient potential receptor melastatin‐2 (TRPM2) channel has emerged as an
important Ca2+ signalling mechanism in a variety of cells, contributing to cellular functions …
important Ca2+ signalling mechanism in a variety of cells, contributing to cellular functions …
TRPM2 channel properties, functions and therapeutic potentials
Importance of the field: Oxidative stress, through production of reactive oxygen species,
triggers disturbance in intracellular calcium [Ca2+] i homeostasis, which has been identified …
triggers disturbance in intracellular calcium [Ca2+] i homeostasis, which has been identified …
Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel
B Tóth, L Csanády - Journal of Biological Chemistry, 2010 - ASBMB
Transient receptor potential melastatin 2 (TRPM2) is a Ca 2+-permeable cation channel
involved in physiological and pathophysiological processes linked to oxidative stress …
involved in physiological and pathophysiological processes linked to oxidative stress …
Intracellular calcium activates TRPM2 and its alternative spliced isoforms
Melastatin-related transient receptor potential channel 2 (TRPM2) is a Ca2+-permeable,
nonselective cation channel that is involved in oxidative stress-induced cell death and …
nonselective cation channel that is involved in oxidative stress-induced cell death and …
The Ca2+‐activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5‐biphosphate
B Nilius, F Mahieu, J Prenen, A Janssens… - The EMBO …, 2006 - embopress.org
Transient receptor potential (TRP) channel, melastatin subfamily (TRPM) 4 is a Ca2+‐
activated monovalent cation channel that depolarizes the plasma membrane and thereby …
activated monovalent cation channel that depolarizes the plasma membrane and thereby …
Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity
TRPM2 is a Ca2+-permeable nonselective cation channel that plays important roles in
oxidative stress–mediated cell death and inflammation processes. However, how TRPM2 is …
oxidative stress–mediated cell death and inflammation processes. However, how TRPM2 is …
Roles of TRPM2 in oxidative stress
N Takahashi, D Kozai, R Kobayashi, M Ebert, Y Mori - Cell calcium, 2011 - Elsevier
Reactive oxygen species (ROS) play critical roles in cell death, diseases, and normal
cellular processes. TRPM2 is a member of transient receptor potential (TRP) protein …
cellular processes. TRPM2 is a member of transient receptor potential (TRP) protein …
Insights into TRPM4 function, regulation and physiological role
R Vennekens, B Nilius - Transient Receptor Potential (TRP) Channels, 2007 - Springer
In the current review we will summarise data from the recent literature describing molecular
and functional properties of TRPM4. Together with TRPM5, these channels are up till now …
and functional properties of TRPM4. Together with TRPM5, these channels are up till now …
TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
M Nazıroğlu - Neurochemical research, 2011 - Springer
Abstract The Na+ and Ca 2+-permeable melastatin related transient receptor potential 2
(TRPM2) channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ or by …
(TRPM2) channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ or by …