Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations
Our understanding of acute lymphoblastic leukemia (ALL) has expanded tremendously in
the past few years because of large-scale genomic studies. 1, 2 ALL is characterized by a …
the past few years because of large-scale genomic studies. 1, 2 ALL is characterized by a …
[HTML][HTML] Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling
Y Watatani, Y Sato, H Miyoshi, K Sakamoto, K Nishida… - Leukemia, 2019 - nature.com
Peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) is a diagnosis of
exclusion, being the most common entity in mature T-cell neoplasms, and its molecular …
exclusion, being the most common entity in mature T-cell neoplasms, and its molecular …
Genomic signatures in T-cell lymphoma: How can these improve precision in diagnosis and inform prognosis?
J Iqbal, R Wilcox, H Naushad, J Rohr, TB Heavican… - Blood reviews, 2016 - Elsevier
The novel genetic information gained from genome-wide high throughput techniques has
greatly improved our understanding of peripheral T-cell lymphoma (PTCL). PTCL consists of …
greatly improved our understanding of peripheral T-cell lymphoma (PTCL). PTCL consists of …
T-cell lymphoblastic lymphoma and leukemia: different diseases from a common premalignant progenitor?
E Kroeze, JLC Loeffen, VM Poort… - Blood …, 2020 - ashpublications.org
T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) represent
malignancies that arise from the transformation of immature precursor T cells. Similarities in …
malignancies that arise from the transformation of immature precursor T cells. Similarities in …
Clonal evolution of adult T-cell leukemia/lymphoma takes place in the lymph nodes
A Umino, M Nakagawa, A Utsunomiya… - Blood, The Journal …, 2011 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATLL) is the neoplasm caused by human T-cell leukemia
virus type 1 (HTLV-1). We performed oligo-array comparative genomic hybridization (CGH) …
virus type 1 (HTLV-1). We performed oligo-array comparative genomic hybridization (CGH) …
[HTML][HTML] Molecular hallmarks of adult T cell leukemia
M Yamagishi, T Watanabe - Frontiers in microbiology, 2012 - frontiersin.org
The molecular hallmarks of adult T cell leukemia (ATL) comprise outstanding deregulations
of signaling pathways that control the cell cycle, resistance to apoptosis, and proliferation of …
of signaling pathways that control the cell cycle, resistance to apoptosis, and proliferation of …
Shared acquired genomic changes in zebrafish and human T-ALL
LA Rudner, KH Brown, KP Dobrinski, DF Bradley… - Oncogene, 2011 - nature.com
T-cell acute lymphoblastic leukemia (T-ALL) is a challenging clinical entity with high rates of
induction failure and relapse. To discover the genetic changes occurring in T-ALL, and those …
induction failure and relapse. To discover the genetic changes occurring in T-ALL, and those …
T‐cell lymphoblastic lymphoma shows differences and similarities with T‐cell acute lymphoblastic leukemia by genomic and gene expression analyses
K Basso, L Mussolin, A Lettieri… - Genes …, 2011 - Wiley Online Library
T‐cell acute lymphoblastic leukemia (T‐ALL) and lymphoma (T‐LBL) share common
morphological and immunophenotypic features and are treated with similar therapeutic …
morphological and immunophenotypic features and are treated with similar therapeutic …
Integrative genomic profiling reveals conserved genetic mechanisms for tumorigenesis in common entities of non‐Hodgkin's lymphoma
MR Green, C Aya‐Bonilla, MK Gandhi… - Genes …, 2011 - Wiley Online Library
Recent developments in genomic technologies have resulted in increased understanding of
pathogenic mechanisms and emphasized the importance of central survival pathways. Here …
pathogenic mechanisms and emphasized the importance of central survival pathways. Here …
Variegated RHOA mutations in adult T-cell leukemia/lymphoma
Y Nagata, K Kontani, T Enami… - Blood, The Journal …, 2016 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATLL) is a distinct form of peripheral T-cell lymphoma with
poor prognosis, which is caused by the human T-lymphotropic virus type 1 (HTLV-1). In …
poor prognosis, which is caused by the human T-lymphotropic virus type 1 (HTLV-1). In …