[PDF][PDF] Cholesteryl Ester Transfer Protein (CETP) Concentration: a Genome-wide Association Study followed by Mendelian Randomization on Coronary Artery Disease

R Li-Gao - OMICS profiling of cardiometabolic diseases - scholarlypublications …
Background—We aimed to identify independent genetic determinants of circulating
cholesteryl ester transfer protein (CETP) to assess causal effects of variation in CETP …

CETP (cholesteryl ester transfer protein) concentration: a genome-wide association study followed by Mendelian randomization on coronary artery disease

LL Blauw, R Li-Gao, R Noordam… - Circulation: Genomic …, 2018 - Am Heart Assoc
Background: We aimed to identify independent genetic determinants of circulating CETP
(cholesteryl ester transfer protein) to assess causal effects of variation in CETP …

[PDF][PDF] CETP concentration: a genome-wide association study followed by Mendelian randomization on coronary artery disease

LL Blauw, R Li-Gao, R Noordam… - Genetic …, 2018 - scholarlypublications …
The genetic basis of circulating cholesteryl ester transfer protein (CETP) concentration is
largely unknown. We aimed to identify independent genetic determinants of circulating …

Mendelian randomization reveals unexpected effects of CETP on the lipoprotein profile

LL Blauw, R Noordam, S Soidinsalo… - European Journal of …, 2019 - nature.com
According to the current dogma, cholesteryl ester transfer protein (CETP) decreases high-
density lipoprotein (HDL)-cholesterol (C) and increases low-density lipoprotein (LDL)-C …

[HTML][HTML] A meta-analytic evaluation of cholesteryl ester transfer protein (CETP) C-629A polymorphism in association with coronary heart disease risk and lipid changes

S Lin, R Dai, R Lin - Oncotarget, 2017 - ncbi.nlm.nih.gov
Lipid metabolism plays an essential role in the pathogenesis of atherosclerosis, a major
cause for coronary heart disease (CHD). Cholesteryl ester transfer protein (CETP) is an …

Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk

A Thompson, E Di Angelantonio, N Sarwar, S Erqou… - Jama, 2008 - jamanetwork.com
Context The importance of the cholesteryl ester transfer protein (CETP) pathway in coronary
disease is uncertain. Study of CETP genotypes can help better understand the relevance of …

Association of CETP gene variants with risk for vascular and nonvascular diseases among Chinese adults

IY Millwood, DA Bennett, MV Holmes, R Boxall… - JAMA …, 2018 - jamanetwork.com
Importance Increasing levels of high-density lipoprotein (HDL) cholesterol through
pharmacologic inhibition of cholesteryl ester transfer protein (CETP) is a potentially …

The effect of cholesteryl ester transfer protein (CETP) activity on cardiometabolic and non-cardiometabolic diseases in East-Asian and European populations

D Dunca, S Chopade… - …, 2023 - atherosclerosis-journal.com
Methods: We selected variants associated with LDL-C and HDL-C from within and
around±50 kbp of the CETP locus from European (n= 1,320,016) and East-Asian (n …

Circulating cholesteryl ester transfer protein and coronary heart disease: mendelian randomization meta-analysis

W Niu, Y Qi - Circulation: Cardiovascular Genetics, 2015 - Am Heart Assoc
Background—The cholesteryl ester transfer protein (CETP) plays a central role in reverse
cholesterol transport. Currently, it remains unresolved whether circulating CETP is causally …

CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease

JF Thompson, LK Durham, ME Lira, C Shear, PM Milos - Atherosclerosis, 2005 - Elsevier
To better understand the role of cholesteryl ester transfer protein (CETP) in cardiovascular
disease, nine polymorphisms spanning the gene from the upstream promoter region to …