The purpose of this study was to analyze the association between the severity of
inflammatory endplate changes (Modic) on MRI and the clinical response to intradiscal …

Purpose Our purpose was to evaluate whether Modic changes (MC) revealed in lumbar MRI
are associated with increased tracer uptake shown in bone scintigraphy. To our knowledge …

Introduction This prospective magnetic resonance imaging (MRI) study in chronic low-back
pain (CLBP) patients evaluated the natural course of degenerative lumbar spine changes in …

Introduction Low back pain is one of the most common causes of seeking medical attention
in industrialized western countries. End plate degenerative changes in the acute phase …

Study Design. Exploratory subgroup analyses of a randomised trial [Antibiotics in Modic
changes (AIM) study]. Objective. The aim was to assess the effect of amoxicillin versus …

Modic changes are of increasing interest, however their age and gender prevalence are not
well described. To date, the associations between Modic changes and other common …

Abstract Only a small proportion (20%) of patients with LBP can be diagnosed based on a
patho-anatomical entity. Therefore, the identification of relevant subgroups, preferably on a …

It is believed that disc degeneration (DD) is, in general, only mildly associated with low back
pain (LBP). MRI-identified Modic changes (MC), probably a late stage of DD, are relatively …

OBJECTIVES: The objective of the current study was to compare short-and long-term effect
on chronic low back pain of intradiscal injection of methylprednisolone with or without …

Vertebral endplate signal changes (VESC), also known as Modic changes, have been
reported to be associated with low back pain (LBP). However, little is known about …