The monoclonal antibody methodology was used to identify membrane structures involved
in T cell functions. To optimize chances to produce and detect relevant antibodies, a …

We screened monoclonal antibodies obtained by xenogeneic immunization for their
capacity to inhibit T cell-mediated cytolysis. These antibodies fell into two classes according …

The appearance of specific cytolytic T lymphocytes (CTL) is a prominent feature of cell-
mediated immune responses to viral infections and to aliografts. CTL kill their target cells …

The cell-mediated cytotoxicity (CMC) of nonadherent cells from the peritoneal cavity (NAPC)
of alloimmunized mice can be measured by the [3H] proline microassay. The exhibition of …

Monoclonal antibodies (mAb) derived from BALB/c mice immunized with human anti‐HLA‐
A2 cloned cytotoxic T lymphocytes (CTL) were screened for their ability to block, in the …

Abstract Two monoclonal anti-Thy-1.2 antibodies were investigated for their activity in
eliminating T cells in vitro and in vivo. Both antibodies exert a complement-dependent cell …

Lymphocyte activation induces or increases the expression of several surface structures,
some of which are directly involved in cell growth such as receptors for IL-2 or transferrin. In …

The Thy-l. 1 molecule was isolated from the BW5147 murine lymphoblastoid cell line. The
initial step in purification was the preparation of a crude plasma membrane fraction followed …

A monoclonal antibody against T200 glycoprotein is selectively cytotoxic for thymocytes and
mature thymus-dependent (T) lymphocytes. All T-cell functions assayed, cell-mediated …

Experiments using conventional antisera1, 2 and monoclonal antibodies3–5 have shown
that there are two functionally distinct human T-cell subsets which express unique cell …