The expression of proinflammatory cytokines and matrix metalloproteinases in the synovial membranes of patients with osteoarthritis compared with traumatic knee …

GI Wassilew, U Lehnigk, GN Duda, WR Taylor… - … : The Journal of …, 2010 - Elsevier
PURPOSE: The aim of this study was to evaluate a subset of matrix metalloproteinases
(MMPs) and proinflammatory cytokines within the synovium, from traumatic knee disorders …

Diverse expression of selected cytokines and proteinases in synovial fluid obtained from osteoarthritic and healthy human knee joints

M Sauerschnig, J Stolberg-Stolberg, A Schulze… - European Journal of …, 2014 - Springer
Background Osteoarthritis (OA) is defined by signs and symptoms of inflammation within the
affected joint. The aim of this study is to determine the mRNA expression levels of selected …

Analysis of the cell infiltrate and expression of proinflammatory cytokines and matrix metalloproteinases in arthroscopic synovial biopsies: comparison with synovial …

TJM Smeets, EC Barg, MC Kraan, MD Smith… - Annals of the …, 2003 - ard.bmj.com
Background: Synovial tissue (ST) from end stage destructive rheumatoid arthritis (RA) and
arthroscopic biopsies obtained during active inflammation might exhibit different …

Increased level of cytokines and matrix metalloproteinases in osteoarthritic subchondral bone

H Hulejova, V Barešová, Z Klézl, M Polanská, M Adam… - Cytokine, 2007 - Elsevier
Objective: The aim of this study was to investigate the expression of several cytokines, matrix
metalloproteinases (MMPs), and tissue inhibitor of matrix metalloproteinases (TIMP)-1 in …

Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee: correlating magnetic resonance imaging findings with disease …

D Loeuille, I Chary‐Valckenaere… - Arthritis & …, 2005 - Wiley Online Library
Objective To determine the magnetic resonance imaging (MRI), macroscopic, and
microscopic characteristics of synovial membrane inflammation, to study the relationship …

Synovial membrane inflammation and cytokine production in patients with early osteoarthritis.

MD Smith, S Triantafillou, A Parker… - The Journal of …, 1997 - europepmc.org
Objective To establish the presence of inflammation in and cytokine production by synovial
membranes from patients with various stages of early osteoarthritis (OA), with knee pain …

Synovial tissue inflammation in early and late osteoarthritis

MJ Benito, DJ Veale, O FitzGerald… - Annals of the …, 2005 - ard.bmj.com
Objective: To compare selected immunohistological features of inflammation in synovial
tissue from patients with early and late osteoarthritis (OA). Methods: Synovial tissue samples …

Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis

YT Konttinen, M Ainola, H Valleala, J Ma… - Annals of the …, 1999 - ard.bmj.com
OBJECTIVE To define the pattern of mRNA expression of all human matrix
metalloproteinases (MMPs) described to date in rheumatoid arthritis (RA) and traumatic …

Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: associations with degenerative changes

LC Tetlow, DJ Adlam, DE Woolley - Arthritis & Rheumatism, 2001 - Wiley Online Library
Objective To examine by immunohistochemistry the relative distributions of 6 matrix
metalloproteinases (MMPs 1, 2, 3, 8, 9, and 13) and the 2 proinflammatory cytokines …

Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two‐year prospective study (the DAMAGE study cohort)

BW Kirkham, MN Lassere, JP Edmonds… - Arthritis & …, 2006 - Wiley Online Library
Objective The primary aim of this prospective 2‐year study was to explain the wide variability
in joint damage progression in patients with rheumatoid arthritis (RA) from measures of …