Efficacy of elbasvir and grazoprevir in participants with hepatitis C virus genotype 4 infection: a pooled analysis

T Asselah, H Reesink, J Gerstoft… - Liver …, 2018 - Wiley Online Library
Abstract Background & Aims The aim of this integrated analysis was to assess the efficacy of
the once‐daily combination of elbasvir 50 mg and grazoprevir 100 mg, with and without …

The safety and efficacy of elbasvir and grazoprevir in participants with hepatitis C virus genotype 1b infection

S Zeuzem, L Serfaty, J Vierling, W Cheng… - Journal of …, 2018 - Springer
Background Genotype 1b (GT1b) is the most common subtype of the hepatitis C virus (HCV).
We present an integrated analysis of 1070 participants with HCV GT1b infection from 30 …

Efficacy and safety of 12 weeks of elbasvir±grazoprevir±ribavirin in participants with hepatitis C virus genotype 2, 4, 5 or 6 infection: The C‐SCAPE study

A Brown, C Hézode, E Zuckerman… - Journal of Viral …, 2018 - Wiley Online Library
People with hepatitis C virus (HCV) infection other than genotype 1 represent a
heterogeneous group. The aim of the phase 2 C‐SCAPE study was to evaluate …

Effectiveness of elbasvir and grazoprevir combination, with or without ribavirin, for treatment-experienced patients with chronic hepatitis C infection

P Kwo, EJ Gane, CY Peng, B Pearlman, JM Vierling… - Gastroenterology, 2017 - Elsevier
Background & Aims Patients infected with hepatitis C virus (HCV) genotype 1, 4, or 6, with or
without cirrhosis, previously treated with peg-interferon and ribavirin, are a challenge to …

Efficacy and safety of elbasvir/grazoprevir for 8 or 12 weeks for hepatitis C virus genotype 4 infection: A randomized study

T Asselah, S Pol, C Hezode, V Loustaud‐Ratti… - Liver …, 2020 - Wiley Online Library
Abstract Background & Aims Hepatitis C virus (HCV) genotype (GT) 4 infection is prevalent
in sub‐Saharan Africa and the Middle East, particularly in Egypt. This study evaluated the …

Efficacy of 12 or 18 weeks of elbasvir plus grazoprevir with ribavirin in treatment‐naïve, noncirrhotic HCV genotype 3‐infected patients

E Gane, R Nahass, V Luketic… - Journal of viral …, 2017 - Wiley Online Library
Summary Elbasvir (EBR; HCV NS 5A inhibitor) and grazoprevir (GZR; HCV NS 3/4A
protease inhibitor) are approved as a fixed‐dose combination to treat patients chronically …

Efficacy and safety of elbasvir/grazoprevir in participants with hepatitis C virus genotype 1, 4, or 6 infection from the Asia–Pacific region and Russia: final results from …

L Wei, JD Jia, FS Wang, JQ Niu… - Journal of …, 2019 - Wiley Online Library
Abstract Background and Aim Although treatment with direct‐acting antivirals has
dramatically improved morbidity and mortality attributable to chronic hepatitis C virus …

Regulatory analysis of effects of hepatitis C virus NS5A polymorphisms on efficacy of elbasvir and grazoprevir

TE Komatsu, S Boyd, A Sherwat, LR Tracy, LK Naeger… - Gastroenterology, 2017 - Elsevier
Background & Aims Elbasvir (an NS5A inhibitor) and grazoprevir (an NS3/4A protease
inhibitor) are direct-acting antiviral agents recently approved in the United States for …

[PDF][PDF] Elbasvir/grazoprevir in Asia‐Pacific/Russian participants with chronic hepatitis C virus genotype 1, 4, or 6 infection

J George, E Burnevich, IS Sheen, J Heo… - Hepatology …, 2018 - Wiley Online Library
The prevalence of hepatitis C virus (HCV) infection in Asian countries is high. This study
assessed the efficacy and safety of elbasvir/grazoprevir (EBR/GZR) in participants with HCV …

Real‐world efficacy of elbasvir and grazoprevir for hepatitis C virus (genotype 1): a nationwide, multicenter study by the Japanese Red Cross Hospital Liver Study …

T Mashiba, K Joko, M Kurosaki, H Ochi… - Hepatology …, 2019 - Wiley Online Library
Aim The present study aimed to determine the real‐world efficacy and safety of the non‐
structural protein (NS) 5A inhibitor elbasvir (EBR) combined with the NS3/4A protease …