Recent updates on novel therapeutic targets of cardiovascular diseases

M Afzal - Molecular and Cellular Biochemistry, 2021 - Springer
In recent times cardiovascular diseases (CVDs) are the leading cause of mortality
universally, caused more or less 17.7 million casualties with 45% of all illnesses (except …

Circulatory therapeutics: use of antihypertensive agents and their effects on the vasculature

EL Schiffrin - Journal of cellular and molecular medicine, 2010 - Wiley Online Library
Antihypertensive agents‐Diuretics‐β‐blockers‐Calcium channel blockers‐Angiotensin
converting enzyme inhibitors‐Angiotensin receptor blockers‐ACEIs versus ARBs versus …

Emerging Molecular Determinants and Protective Strategies in Heart Disease: What's New in the Journal of Clinical Medicine? Outlook to the Future

C Rocca, T Angelone - Journal of Clinical Medicine, 2023 - mdpi.com
Cardiovascular diseases (CVD), including coronary heart disease (CHD), heart attacks,
stroke, heart failure (HF), and peripheral artery disease, still represent the leading cause of …

Future horizons in cardiovascular molecular therapeutics

VJ Dzau, GH Gibbons, M Mann… - The American journal of …, 1997 - Elsevier
In the past 2 decades, significant progress has been made in cardiovascular therapeutics.
Effective drug therapies have been developed for hypertension, hypercholesterolemia …

Pathophysiology and pharmacotherapy of cardiovascular disease

G Jagadeesh, P Balakumar, K Maung-U - 2015 - Springer
The present book covers the basic principles of cardiovascular physiology, pathophysiology
and advanced pharmacology with particular emphasis on cellular mechanisms of drug …

The grand challenges in cardiovascular drug discovery and development

EH Ohlstein - Frontiers in pharmacology, 2010 - frontiersin.org
Despite the major advancements in cardiovascular medicine over the past 50 years, heart
disease and stroke remain the number one public health concern and primary causes of …

[HTML][HTML] Biologics and cardiac disease: challenges and opportunities

G Ciucci, A Colliva, R Vuerich, G Pompilio… - Trends in …, 2022 - cell.com
Biologics are revolutionizing the treatment of chronic diseases, such as cancer and
monogenic disorders, by overcoming the limits of classic therapeutic approaches using …

The grand challenge of discovering new cardiovascular drugs

CC Hong - Frontiers in drug discovery, 2022 - frontiersin.org
Background Heart disease is the# 1 killer worldwide, greater than all cancers combined.
This is despite the fact that, in the developed world, there has been a substantial decline in …

Recent advances in cardiovascular pharmacology

WH Frishman - Current Problems in Cardiology, 2000 - Elsevier
Introduction espite the large number of pharmacologic agents available for the treatment of
cardiovascular disease, the search for additional drugs and pharmacotherapeutic …

New and emerging cardiovascular and antihypertensive drugs

SG Chrysant, GS Chrysant - Expert Opinion on Drug Safety, 2020 - Taylor & Francis
Introduction Hypertension and cardiovascular diseases (CVD) are very common conditions
and account for significant medical disability and death worldwide. Therefore, their …