aminothiophene derivatives (2AT) in which the thiophene ring is fused with a cycloalkyl or a
N‐acylated piperidine ring by positions 5 and 6 and carrying a 3‐carbethoxy group were …

The role of Staphylococcal efflux pump in antibiotics and biocides resistance considered
global issue and finding cheap, easy to handling and nontoxic efflux pump inhibitors is a …

Naphthyridines represent a class of heterocyclic compounds formed by two condensed
aromatic rings. This study aimed to evaluate the antibacterial activity and in vitro inhibition of …

The thiopyranopyridine moiety was synthesized as a new heterocyclic base to be inserted at
the C-7 position of selected quinolone nuclei followed by a determination of antibacterial …

The emergence of multidrug-resistant Staphylococcus aureus coupled with a declining
output of new antibiotic treatment options from the pharmaceutical industry is a growing …

Staphylococcus aureus has developed resistance to antimicrobials since their first use. The
S. aureus major facilitator superfamily (MFS) efflux pump Tet (K) contributes to resistance to …

A new series of 3-(substituted-3, 4-dihydronaphthyl)-2-propenoic acid amides has been
prepared through convergent synthetic strategies and tested in combination with …

Resistance of microorganisms to many classes of antibiotics and other drugs has become a
serious problem of public health. Multidrug resistance (MDR) is increasingly prevalent …

This study aimed to evaluate the antibacterial activity and to verify, in silico and in vitro, the
inhibition of efflux mechanisms using a series of synthesized 1, 8-naphthyridines …

The anti-microbial activity of six non-antibiotics (one amino-ethylchloride, three
phenothiazines, two tricyclic antidepressives) were tested on 20 clinical isolates of …