THE APPLICATION OF CANNABIDIOL IN THE TREATMENT OF GLIOBLASTOMA.
A RYBARCZYK… - Acta Poloniae …, 2023 - search.ebscohost.com
Glioblastoma multiforme (GBM), a high-grade astrocytoma, is an incurable brain tumor
associated with genetic heterogeneity and dysregulated signaling pathways. As alternations …
associated with genetic heterogeneity and dysregulated signaling pathways. As alternations …
[HTML][HTML] Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: Novel anti-tumor mechanisms of Cannabidiol in breast cancer
The anti-tumor role and mechanisms of Cannabidiol (CBD), a non-psychotropic cannabinoid
compound, are not well studied especially in triple-negative breast cancer (TNBC). In the …
compound, are not well studied especially in triple-negative breast cancer (TNBC). In the …
Targeting multiple cannabinoid anti‐tumour pathways with a resorcinol derivative leads to inhibition of advanced stages of breast cancer
R Murase, R Kawamura, E Singer… - British journal of …, 2014 - Wiley Online Library
Background and Purpose The psychoactive cannabinoid Δ9‐tetrahydrocannabinol (THC)
and the non‐psychoactive cannabinoid cannabidiol (CBD) can both reduce cancer …
and the non‐psychoactive cannabinoid cannabidiol (CBD) can both reduce cancer …
Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
The aggressive behavior of Glioblastoma multiforme (GBM) is mainly due to high
invasiveness and proliferation rate as well as to high resistance to standard chemotherapy …
invasiveness and proliferation rate as well as to high resistance to standard chemotherapy …
The antitumor action of endocannabinoids in the tumor microenvironment of glioblastoma
Y Tang, M Wang, J Yu, G Lv, Y Wang… - Frontiers in …, 2024 - frontiersin.org
Approximately 80% of all malignant brain tumors are gliomas, which are primary brain
tumors. The most prevalent subtype of glioma, glioblastoma multiforme (GBM), is also the …
tumors. The most prevalent subtype of glioma, glioblastoma multiforme (GBM), is also the …
Repurposing cannabidiol as a potential drug candidate for anti-tumor therapies
F Wang, G Multhoff - Biomolecules, 2021 - mdpi.com
In recent years, evidence has accumulated that cannabinoids—especially the non-
psychoactive compound, cannabidiol (CBD)—possess promising medical and …
psychoactive compound, cannabidiol (CBD)—possess promising medical and …
[HTML][HTML] Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration
M Nabissi, MB Morelli, M Offidani, C Amantini… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Several studies showed a potential anti-tumor role for cannabinoids, by modulating cell
signaling pathways involved in cancer cell proliferation, chemo-resistance and migration …
signaling pathways involved in cancer cell proliferation, chemo-resistance and migration …
Bipiperidinyl Derivatives of Cannabidiol Enhance Its Antiproliferative Effects in Melanoma Cells
P Lyu, H Li, J Wan, Y Chen, Z Zhang, P Wu, Y Wan… - Antioxidants, 2024 - mdpi.com
Cannabis and its major cannabinoid cannabidiol (CBD) are reported to exhibit anticancer
activity against skin tumors. However, the cytotoxic effects of other minor cannabinoids and …
activity against skin tumors. However, the cytotoxic effects of other minor cannabinoids and …
5‐Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non‐psychoactive cannabinoid
P Massi, M Valenti, A Vaccani, V Gasperi… - Journal of …, 2008 - Wiley Online Library
It has been recently reported that cannabidiol (CBD), a non‐psychoactive cannabinoid, is
able to kill glioma cells, both in vivo and in vitro, independently of cannabinoid receptor …
able to kill glioma cells, both in vivo and in vitro, independently of cannabinoid receptor …
Synthetic cannabinoids influence the invasion of glioblastoma cell lines in a cell-and receptor-dependent manner
T Hohmann, K Feese, T Greither, C Ghadban, V Jäger… - Cancers, 2019 - mdpi.com
The current treatment of glioblastoma is not sufficient, since they are heterogeneous and
often resistant to chemotherapy. Earlier studies demonstrated effects of specific cannabinoid …
often resistant to chemotherapy. Earlier studies demonstrated effects of specific cannabinoid …