Toll-like receptors (TLRs) are important signal transducers that mediate inflammatory
reactions induced by microbes through pattern recognition of virulence molecules such as …

The lipopolysaccharide (LPS) and fimbriae of Porphyromonas gingivalis play important roles
in periodontal inflammation and pathogenesis. We investigated fimbriae and LPS from …

Bacterial fimbriae are an important pathogenic factor. It has been demonstrated that fimbrial
protein encoded by fimA gene (FimA fimbriae) of Porphyromonas gingivalis not only …

The fimbriae of the oral pathogen Porphyromonas gingivalis induce Toll-like receptor 2
(TLR2)-dependent macrophage activation upon their recognition by CD14 and the β 2 …

Gingival epithelial cells are a central component of the barrier between oral microflora and
internal tissues. Host responses to periodontopathic bacteria and surface components …

CD11b–CD18 and other integrins play important roles in immunity and inflammation and
require prior activation through inside‐out signaling to efficiently bind their ligands. We …

Toll‐like receptors (TLRs) and other pattern‐recognition receptors (PRRs) of the innate
immune system form functional receptor complexes that recognize and respond to pathogen …

Members of the Toll-like receptor (TLR) family are components of the mammalian anti-
microbial response, signaling with a domain closely related to that of IL-1 receptors. In this …

Bacterial fimbriae are associated with a specific adherence factor, adhesin, in their microbial
etiology. Porphyromonas gingivalis, as an anaerobic Gram‐negative periodontopathogenic …

Fimbriae target bacteria to different mucosal surfaces and enhance the inflammatory
response at these sites. Inflammation may be triggered by the fimbriae themselves or by …