Inflammatory bowel disease: is the intestine a Trojan horse?

C Basset, J Holton - Science progress, 2002 - journals.sagepub.com
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory condition of the
intestines that is clinically heterogenous. The cause (s) of IBD are currently unknown but the …

Immunopathophysiology of inflammatory bowel disease: how genetics link barrier dysfunction and innate immunity to inflammation

M Mehta, S Ahmed, G Dryden - Innate immunity, 2017 - journals.sagepub.com
Inflammatory bowel diseases (IBD) comprise a distinct set of clinical symptoms resulting
from chronic or relapsing immune activation and corresponding inflammation within the …

Immunopathogenesis of inflammatory bowel disease

J Matricon, N Barnich, D Ardid - Self/nonself, 2010 - Taylor & Francis
Inflammatory bowel disease (IBD) is a group of idiopathic, chronic and relapsing
inflammatory conditions of the gastrointestinal tract. Familial and epidemiological studies …

Importance of bacteria as trigger in inflammatory bowel disease

J Denizot, N Dreux, A Darfeuille-Michaud… - … of Gastrointestinal & …, 2012 - uca.hal.science
Inflammatory bowel diseases (IBD) provide a complex model of host-microbe interactions
underpinning disease pathogenesis. Although there is no widespread agreement on the …

Intestinal barrier dysfunction in inflammatory bowel diseases

MA McGuckin, R Eri, LA Simms… - Inflammatory bowel …, 2009 - academic.oup.com
The etiology of human inflammatory bowel diseases (IBDs) is believed to involve
inappropriate host responses to the complex commensal microbial flora in the gut, although …

Inflammatory bowel disease: the classic gastrointestinal autoimmune disease

A Kaistha, J Levine - Current problems in pediatric and adolescent health …, 2014 - Elsevier
Inflammatory bowel disease (IBD) is an idiopathic disease thought to be caused by a
dysregulated immune response to host intestinal microflora. The role of genetic factors is …

Immunopathogenesis of inflammatory bowel disease: role of cytokines and immune cell-enterocyte interactions

S Dionne, FM Ruemmele, EG Seidman - Inflammatory bowel diseases, 1999 - karger.com
For over half a century, and despite progressively intensified research efforts, the etiology of
inflammatory bowel disease remains an enigma. The most widely accepted comprehensive …

[HTML][HTML] Current concepts of the pathogenesis of inflammatory bowel disease

J Rask-Madsen - World Journal of Gastroenterology, 1998 - wjgnet.com
Over the past decade, the focus of the etiopathogenesis of chronic inflammatory bowel
disease (IBD) has turned toward defining a deficit in immune regulation. The problem …

Inflammation in the intestinal tract: pathogenesis and treatment

RS Blumberg - Digestive diseases, 2009 - karger.com
Over the past decade a major hypothesis has emerged for the etiopathogenesis of
inflammatory bowel disease (IBD). This hypothesis proposes that IBD represents a …

Genetics and innate and adaptive immunity in IBD

G Zanello, D Kevans, A Goethel, M Silverberg… - … , Gut Microbiota and …, 2014 - karger.com
Inflammatory bowel disease (IBD) is an abnormal inflammatory response within the gut to a
trigger that has yet to be identified. The family history in many patients, especially those with …