β 2-glycoprotein I (β 2 GPI) is an abundant multidomain plasma protein that plays various
roles in the clotting and complement cascades. It is also the main target of antiphospholipid …

β 2-Glycoprotein I (β 2 GPI) is an abundant plasma protein displaying phospholipid-binding
properties. Because it binds phospholipids, it is a target of antiphospholipid antibodies …

Background Antiphospholipid antibodies targeting β 2-glycoprotein I (β 2 GPI) cause
thrombosis and pregnancy morbidity in antiphospholipid syndrome (APS) patients. How …

The human plasma protein β2-glycoprotein I (β2-GPI) is the major target of autoantibodies
associated with antiphospholipid syndrome. However, the biologic function of this abundant …

In an attempt to understand the multifunctional involvement of β2-glycoprotein I (β2GPI) in
autoimmune diseases, thrombosis, atherosclerosis, and inflammatory processes, substantial …

β2-Glycoprotein I (β2-GPI), which consists of four complement control protein modules and a
distinctly folded fifth C-terminal domain, is an essential cofactor for the binding to …

To understand the mechanism of the interaction between human β2-glycoprotein I (β2-GPI)
and negatively charged phospholipids, we determined the three-dimensional solution …

The antiphospholipid syndrome (APS) is an autoimmune disease characterised by a
procoagulant state that predisposes to recurrent thrombosis and miscarriages. Two major …

Summary β 2‐Glycoprotein I (β 2‐GPI) is a protein that circulates in blood at high
concentrations. The function of β 2‐GPI has long been an enigma. More than 20 years ago …

β2-Glycoprotein I (β2GpI) is the major autoantigen in the antiphospholipid syndrome, a
thrombotic autoimmune disease. Nonetheless, the physiological role of β2GpI is still unclear …